Merck
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AP113P

Sigma-Aldrich

Goat Anti-Human IgG Antibody, Fc, HRP conjugate

Chemicon®, from goat

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eCl@ss:
32160702
NACRES:
NA.46

Nivel de calidad

100

origen biológico

goat

conjugado

peroxidase conjugate

forma del anticuerpo

F(ab′)2 fragment of affinity isolated antibody

antibody product type

secondary antibodies

clon

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

enviado en

wet ice

Categorías relacionadas

Descripción general

Immunoglobulin G (IgG) is the most common antibody isotype found in the human serum. It exists in four isotypes IgG1, IgG2, IgG3, and IgG4. IgG structure is characterized with four polypeptide chains with two identical heavy (H) chains and two identical λ light (L) chains. These chains are inter-linked by disulfide bonds. IgG is produced by the B cells.

Inmunógeno

Human IgG

Aplicación

Goat Anti-Human IgG Antibody, Fc, HRP conjugate has been used in enzyme linked immunosorbent assay (ELISA)(1:3,000).
It is also suitable for use in:
  • enzyme immunoassay (EIA) with OPD: 1:5,000-1:100,000
  • immunohistochemistry 1:500-1:5,000
  • western blot

Acciones bioquímicas o fisiológicas

Immunoglobulin G (IgG) is implicated in antibody-dependent cell-mediated cytotoxicity (ADCC). It aids in the activation of the classical pathway of the complement system. It neutralizes virus particles and toxins. Maternal IgG is transferred to the fetus through the placenta that is crucial for protecting newborns against infectious diseases. Measurement of IgG levels in severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2 infected patients can be used as a potential strategy to assess the severity and prognosis of coronavirus disease 2019 (COVID‐19).

Forma física

Lyophilized. Buffer = 0.01 M Sodium Phosphate, 0.25 M NaCl, pH 7.6 with 15 mg/mL BSA. Contains no preservative.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Certificado de Análisis

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Certificado de calidad

Introduzca el número de lote para buscar un certificado de calidad (COQ).

Presupuestos y pedidos

Bulk Quote-Order Product
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We have developed a rapid, accurate, and cost-effective serologic test for SARS-CoV-2 virus, which caused the COVID-19 pandemic, on the basis of antibody-dependent agglutination of antigen-coated latex particles. When validated using plasma samples that are positive or negative for SARS-CoV-2
Mengyan Li et al.
The Journal of clinical investigation, 131(23) (2021-10-22)
To delineate the in vivo role of different costimulatory signals in activating and expanding highly functional virus-specific cytotoxic CD8+ T cells, we designed synTacs, infusible biologics that recapitulate antigen-specific T cell activation signals delivered by antigen-presenting cells. We constructed synTacs
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Testing null
Tara Bancroft et al.
Cellular immunology, 304-305, 35-43 (2016-05-24)
The recent increase in cases of whooping cough among teenagers in the US suggests that the acellular Bordetella pertussis vaccine (aP) that became standard in the mid 1990s might be relatively less effective than the whole-bacteria formulation (wP) previously used
Dorothee Winterberg et al.
Journal of clinical medicine, 10(12) (2021-07-03)
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most frequent malignancy in children and also occurs in adulthood. Despite high cure rates, BCP-ALL chemotherapy can be highly toxic. This type of toxicity can most likely be reduced by antibody-based immunotherapy
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