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410225

Glicina

ACS reagent grade, ≥98.5%, powder, crystals or granules

Sinónimos:

Glicocola, Ácido aminoacético, Ácido aminoetanoico

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Fórmula lineal:
NH2CH2COOH
Número CAS:
Peso molecular:
75.07
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-272-2
MDL number:
Beilstein/REAXYS Number:
635782
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Nombre del producto

Glicina, ACS reagent, ≥98.5%

grade

ACS reagent

Quality Level

assay

≥98.5%

form

powder, crystals or granules

impurities

H2SO4, passes test (darkened), Hydrolyzable subsances, passes test

ign. residue

≤0.1%

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.005%

cation traces

NH4+: ≤0.005%, heavy metals: ≤0.002% (by ICP)

application(s)

peptide synthesis

functional group

amine, carboxylic acid

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

General description

Glycine is the simplest amino acid building block.

Application

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.
Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

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Este artículo
G7126G889815527
grade

ACS reagent

grade

-

grade

-

grade

-

form

powder, crystals or granules

form

powder

form

powder

form

crystalline powder

functional group

amine, carboxylic acid

functional group

amine, carboxylic acid

functional group

amine, carboxylic acid

functional group

-

assay

≥98.5%

assay

≥99% (HPLC)

assay

≥99%

assay

99-101% (based on anhydrous substance)

impurities

H2SO4, passes test (darkened), Hydrolyzable subsances, passes test

impurities

≤0.01% Ammonia

impurities

≤0.01% Insoluble matter

impurities

hydrolyzable substances, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤1.0% ninhydrin-positive substances

cation traces

NH4+: ≤0.005%, heavy metals: ≤0.002% (by ICP)

cation traces

≤0.01% (Ammonia (NH3))

cation traces

heavy metals (as Pb): ≤20 ppm

cation traces

-


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Certificados de análisis (COA)

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Controversial Effects of D-Amino Acid Oxidase Activator (DAOA)/G72 on D-Amino Acid Oxidase (DAO) Activity in Human Neuronal, Astrocyte and Kidney Cell Lines: The N-methyl D-aspartate (NMDA) Receptor Hypofunction Point of View
Vinita Jagannath
Frontiers in Molecular Neuroscience (2017)
A Novel Acoustomicrofluidic Nebulization Technique Yielding New Crystallization Morphologies
Heba Ahmed
Advanced Materials, 30(3) (2018)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain
Science, 336(6084), 1040-1044 (2012)



Número de artículo de comercio global

SKUGTIN
410225-1KG04065273586763
410225-50G04061835555123
410225-250G04061835555116

Preguntas

1–2 de 2 Preguntas  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 respuesta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 respuesta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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