Merck
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59924

Sigma-Aldrich

Polysorbate 80

tested according to Ph. Eur.

Synonym(s):
POE (20) sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polyethylene glycol sorbitan monooleate, TWEEN 80, Polysorbate 80, Polysorbatum 80
CAS Number:
Número MDL:
NACRES:
NA.21

Nivel de calidad

200

Agency

USP/NF
tested according to Ph. Eur.

presión de vapor

<1 mmHg ( 20 °C)

descripción

non-ionic

formulario

liquid

mol peso

average mol wt 79,000

número de agregación

60

índice de refracción

n20/D 1.472 (lit.)

CMC

0.012

temperatura de transición

cloud point 65 °C

densidad

1.064 g/mL at 25 °C (lit.)

HLB

15

application(s)

pharmaceutical (small molecule)

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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Descripción general

Polysorbate 80 is a surfactant. Polysorbates are a combination of oleic esters of sorbitol and sorbitanes with polyethylene glycol chains.

Aplicación

Polysorbate 80 has been used in drug (rapamycin) treatment and to study the effect of rapamycin on osteolysis and tumor growth. It has also been used in the preparation of spray-dried emulsions and to study antibacterial efficacy.

Acciones bioquímicas o fisiológicas

Polysorbates is used as emulsifiers, dissolving agents and stabilizer for essential oils, topical application and medical infusions including intravenous, subcutaneous or intramuscular administration.

Información legal

TWEEN is a registered trademark of Croda International PLC

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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