Merck

P4347

Sigma-Aldrich

Propylene Glycol

meets USP testing specifications

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Sinónimos:
1,2-Propanediol
Fórmula lineal:
CH3CH(OH)CH2OH
Número de CAS:
Peso molecular:
76.09
Beilstein:
1340498
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.25

Agency

USP/NF
meets USP testing specifications

Nivel de calidad

densidad de vapor

2.62 (vs air)

presión de vapor

0.08 mmHg ( 20 °C)

temp. de autoignición

779 °F

lim. expl.

12.5 %

índice de refracción

n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

densidad

1.036 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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Este artículo
16033134368Y0001547
Propylene Glycol meets USP testing specifications

Sigma-Aldrich

P4347

Propylene Glycol

1,2-Propanediol meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

Sigma-Aldrich

16033

1,2-Propanediol

1,2-Propanediol ReagentPlus®, 99%

Sigma-Aldrich

134368

1,2-Propanediol

Propylene glycol European Pharmacopoeia (EP) Reference Standard

Y0001547

Propylene glycol

vapor pressure

0.08 mmHg ( 20 °C)

vapor pressure

0.08 mmHg ( 20 °C)

vapor pressure

0.08 mmHg ( 20 °C)

vapor pressure

0.08 mmHg ( 20 °C)

autoignition temp.

779 °F

autoignition temp.

779 °F

autoignition temp.

779 °F

autoignition temp.

779 °F

expl. lim.

12.5 %

expl. lim.

12.5 %

expl. lim.

12.5 %

expl. lim.

12.5 %

refractive index

n20/D 1.432 (lit.)

refractive index

n20/D 1.431-1.433, n20/D 1.432 (lit.)

refractive index

n20/D 1.432 (lit.)

refractive index

n20/D 1.432 (lit.)

bp

187 °C (lit.)

bp

187 °C (lit.)

bp

187 °C (lit.)

bp

187 °C (lit.)

Descripción general

Propylene glycol, a low-molecular-weight aliphatic alcohol, holds significance as a key solvent in biological and pharmaceutical formulation research. Its outstanding miscibility with water and diverse organic compounds, coupled with its low freezing point, low vapor pressure, and non-toxic nature, positions it as a preferred choice for a variety of research applications, particularly in sensitive biological assays and pharmaceutical preparations.

Going beyond its solvent capabilities, propylene glycol excels as an excipient in pharmaceutical formulations, enhancing the solubility and stability of therapeutic molecules and pharmaceutical additives. This attribute proves indispensable in excipient and drug delivery research, contributing to the development of more efficacious and stable medications. In biochemical and physiological research, propylene glycol functions as a potent cryoprotectant, safeguarding cells and tissues from freezing-induced damage. Its application extends to investigations of drug absorption, metabolism, and distribution, providing researchers with a crucial tool to decipher the intricate journey of drugs within the body.

The versatility of propylene glycol extends to molecular biology, particularly in Polymerase Chain Reaction (PCR), where it safeguards DNA and RNA strands, ensuring reliable and reproducible results. Studies demonstrate its exceptional ability to stabilize DNA for extended periods, making it an essential component for long-term sample preservation in genetic and genomic analyses. In the pharmaceutical industry, propylene glycol finds extensive use as a solvent and extraction medium, playing a pivotal role in drug development research, facilitating efficient extraction and purification of bioactive compounds.

Aplicación

Propylene glycol has been used:
  • for removing excess Oil Red O stain in zebrafish larvae
  • in the preparation of alginate hydrogels
  • for the dissolution of androstenone
  • for the calibration of cone beam scanner in computed tomography

Características y beneficios

  • Versatile and adaptable for a wide variety of laboratory and research applications
  • Meets USP testing specifications

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 1

Punto de inflamabilidad F

219.2 °F - closed cup

Punto de inflamabilidad C

104 °C - closed cup

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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T1503
Referencia del producto
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25G
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