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PHR1236

Supelco

Acetato de retinil

Pharmaceutical Secondary Standard; Certified Reference Material

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Sinónimos:
Acetato de retinol, Acetato de vitamina A
Empirical Formula (Hill Notation):
C22H32O2
Número de CAS:
127-47-9
Peso molecular:
328.49
Beilstein:
1915439
Número de EC:
204-844-2
Número MDL:
MFCD00019413
ID de la sustancia en PubChem:
329823241
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

300

Agency

traceable to Ph. Eur. R0300000
traceable to USP 1716002

API family

retinyl compounds

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

57-58 °C

application(s)

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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Este artículo
R030000046958R7882
Retinyl Acetate (Vitamin A Acetate) Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1236

Retinyl Acetate (Vitamin A Acetate)

Retinol acetate European Pharmacopoeia (EP) Reference Standard

R0300000

Retinol acetate

Retinyl acetate analytical standard

Supelco

46958

Retinyl acetate

Retinyl acetate solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

Sigma-Aldrich

R7882

Retinyl acetate

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | mammalian: suitable

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

application(s)

-

format

neat

format

neat

format

neat

format

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-10 to -25°C

storage temp.

−20°C

Quality Level

300

Quality Level

-

Quality Level

100

Quality Level

200

Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Retinyl Acetate belongs to the class of compounds called retinoids, which are chemically related to vitamin A. Retinoids are employed in the management of acne and psoriasis by their administration in oral and topical means.

Aplicación

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB3672 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictogramas

Health hazard
GHS08

Palabra de señalización

Danger

Frases de peligro

H360D - H413

Clasificaciones de peligro

Aquatic Chronic 4 - Repr. 1B

Código de clase de almacenamiento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Las referencias de los producto se combinan con los tamaños de envase y las cantidades cuando se muestran en la página web, por ejemplo: T1503-25G. Asegúrese de introducir el número de producto ÚNICAMENTE en el campo del Número de producto (Ejemplo T1503).

Ejemplo

T1503
Referencia del producto
-
25G
Tamaño del envase/cantidad

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Retinyl acetate solution 100 μg/mL in ethanol (with 0.1% (w/v) BHT; degassed), reference material, Cerilliant®

Supelco

V-040

Retinyl acetate solution

Retinyl Acetate-Water Soluble BioReagent, suitable for cell culture

Sigma-Aldrich

R0635

Retinyl Acetate-Water Soluble

Phytonadione Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1078

Phytonadione

Vitamin A water-miscible 1 ml = 200,000 I.U. for oral use, EMPROVE® ESSENTIAL, Ph. Eur., BP

SAFC

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Retinyl Propionate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1668

Retinyl Propionate

Retinol synthetic, ≥95% (HPLC), crystalline

Sigma-Aldrich

R7632

Retinol

Retinyl palmitate Type IV, ~1,800,000 USP units/g, oil

Sigma-Aldrich

R3375

Retinyl palmitate

DL-alpha-Tocopherol acetate analytical standard

Supelco

47786

DL-alpha-Tocopherol acetate

Inhibitory Effects of Retinoic Acid or Retinyl Acetate on the Growth of Untransformed, Transformed, and Tumor Cells In Vitro
Lotan R and Nicolson GL
Journal of the National Cancer Institute, 59(6), 1717-1722 (1977)
Inhibition of rat mammary carcinogenesis by short dietary exposure to retinyl acetate
McCormick DL, et al.
Cancer research, 40(4), 1140-1143 (1980)
Vademecum for Vitamin Formulations (2001)
Natalia Cernicchiaro et al.
Foodborne pathogens and disease, 7(9), 1071-1081 (2010-05-27)
Alteration of the gastro-intestinal tract through manipulation of cattle diets has been proposed as a preharvest control measure to reduce fecal shedding of Escherichia coli O157:H7. The objective of this study was to examine the effects of the energy source's
Guangwen Tang et al.
The American journal of clinical nutrition, 89(6), 1776-1783 (2009-04-17)
Genetically engineered "Golden Rice" contains up to 35 microg beta-carotene per gram of rice. It is important to determine the vitamin A equivalency of Golden Rice beta-carotene to project the potential effect of this biofortified grain in rice-consuming populations that
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Protocolos

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

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