Merck
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T6399

Sigma-Aldrich

Trichloroacetic acid

ACS reagent, ≥99.0%

Sinónimos:
TCA
Fórmula lineal:
Cl3CCOOH
Número de CAS:
Peso molecular:
163.39
Beilstein:
970119
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.21

Nivel de calidad

200

grado

ACS reagent

densidad de vapor

<1 (vs air)

presión de vapor

1 mmHg ( 51 °C)

ensayo

≥99.0%

impurezas

Substances darkened by sulfuric acid, passes test
≤0.01% insoluble matter

residuo de ign.

≤0.03%

índice de refracción

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubilidad

H2O: 1 g/10 mL

densidad

1.62 g/mL at 25 °C (lit.)

trazas de anión

chloride (Cl-): ≤0.002%
nitrate (NO3-): ≤0.002%
phosphate (PO43-): ≤5 ppm
sulfate (SO42-): ≤0.02%

trazas de catión

Fe: ≤0.001%
heavy metals (as Pb): ≤0.002%

temp. de almacenamiento

2-8°C

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

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Aplicación

  • Trichloroacetic acid has been used for the precipitation of sLRP (soluble circulating low density lipoprotein receptor-related protein-1) isolated from plasma.
  • It has been used for the extraction of ascorbic acid from plant samples. It has also been used for the preparation of ascorbate standards for ascorbate assay.
  • It has been used for the precipitation of IMAC (immobilized metal ion affinity chromatography)-isolated phosphoproteins.
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Envase

5, 100, 4×100, 250, 500 g in glass bottle
1 kg in glass bottle

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 2

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Certificado de Análisis

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Certificado de origen

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Casein Kinase 2 (CK2)-mediated Phosphorylation of Hsp90? as a Novel Mechanism of Rifampin-induced MDR1 Expression.
Kim SW et al.
The Journal of Biological Chemistry, 290, 17029-17029 (2015)
Measurement of reduced, oxidized and total ascorbate content in plants.
Gillespie KM and Ainsworth EA
Nature Protocols, 2, 871-871 (2007)
Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-? is an early biomarker for mild cognitive impairment preceding Alzheimer's disease.
Sagare AP et al.
Journal of Alzheimer'S Disease, 24, 25-25 (2011)
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Journal of Alzheimer's disease : JAD, 70(3), 667-680 (2019-07-01)
Increased levels of total tau (t-tau) and hyperphosphorylated tau (p-tau) proteins in the cerebrospinal fluid of Alzheimer's disease (AD) patients are well documented and strongly correlate with AD pathology. Recent studies have further shown that human tau can be released
Valentina Folgiero et al.
Oncotarget, 5(8), 2052-2064 (2014-06-07)
Microenvironmental factors contribute to the immune dysfunction characterizing acute myeloid leukemia (AML). Indoleamine 2,3-dioxygenase 1 (IDO1) is an interferon (IFN)-γ-inducible enzyme that degrades tryptophan into kynurenine, which, in turn, inhibits effector T cells and promotes regulatory T-cell (Treg) differentiation. It

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