Polymyxin B sulfate for microbiological assay

European Pharmacopoeia (EP) Reference Standard

Polymyxin B sulfate
Número de CAS:


pharmaceutical primary standard





Industria destacada

Pharmaceutical (small molecule)



temp. de almacenamiento




InChI key


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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.


Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.


Otras notas

Sales restrictions may apply.


13 - Non Combustible Solids

WGK Alemania


Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

Mitsuru Ishizuka et al.
Surgery, 156(1), 168-175 (2014-06-16)
Although most patients with septic shock have a poor outcome, some may survive after blood purification treatment such as polymyxin B cartridge hemoperfusion (PMX). To explore the most significant characteristic associated with 28-day mortality in patients with septic shock receiving...
T W Cullen et al.
Science (New York, N.Y.), 347(6218), 170-175 (2015-01-13)
Resilience to host inflammation and other perturbations is a fundamental property of gut microbial communities, yet the underlying mechanisms are not well understood. We have found that human gut microbes from all dominant phyla are resistant to high levels of...
M E Evans et al.
The Annals of pharmacotherapy, 33(9), 960-967 (1999-09-24)
Polymyxin B sulfate and colistin, also known as colistimethate, have not been used for many years because less toxic antimicrobials are available. Gram-negative bacteria that are resistant to the aminoglycosides, beta-lactams, and fluoroquinolones are becoming more common. These bacteria are...
Gary C Port et al.
Journal of bacteriology, 196(14), 2563-2577 (2014-05-06)
The ExPortal protein secretion organelle in Streptococcus pyogenes is an anionic phospholipid-containing membrane microdomain enriched in Sec translocons and postsecretion protein biogenesis factors. Polymyxin B binds to and disrupts ExPortal integrity, resulting in defective secretion of several toxins. To gain...
Polymyxin B hemoperfusion: matching the cure to the disease.
Dinna N Cruz
Critical care medicine, 42(5), 1309-1310 (2014-04-17)

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