Sodium hydroxide

ACS reagent, ≥97.0%, pellets

‘Caustic soda’
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Nivel de calidad



ACS reagent

densidad de vapor

>1 (vs air)

presión de vapor

<18 mmHg ( 20 °C)
3 mmHg ( 37 °C)






cell culture | mammalian: suitable
titration: suitable


≤0.001% N compounds
≤0.02% NH4OH ppt.
≤1.0% Na2CO3


318 °C (lit.)


water: soluble 1,260 g/L at 20 °C


2.13 g/cm3 at 20 °C

trazas de anión

chloride (Cl-): ≤0.005%
phosphate (PO43-): ≤0.001%
sulfate (SO42-): ≤0.003%

trazas de catión

Fe: ≤0.001%
Hg: ≤0.1 ppm
K: ≤0.02%
Ni: ≤0.001%
heavy metals (as Ag): ≤0.002%

SMILES string




InChI key


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Descripción general

Sodium hydroxide (NaOH) also known as caustic soda is a water soluble inorganic base with a wide range of industrial application such as titration, dissolution testing and in impinger to remove acidic gases. It participates in the oxidation of glycerol catalyzed by Au/charcoal or Au/graphite. It participates in solvent-free aldol condensation reaction.


Sodium hydroxide may be used as a base in titration methods, dissolution testing, for adjusting pH and in the impinger to remove acidic gases.
It may be used in the following processes:
  • Conversion of glycerol to glyceric acid in the presence of gold catalyst.
  • Palladium-catalyzed cross-coupling reaction between vinylalkoxysilanes and aryl bromides or chlorides to form styrenes.
Sodium hydroxide (NaOH) was used in the following processes:
  • Preparation of sodium 3,3′-bis(sulfonato)-4,4′-bis(chloroacetamido)azobenzene (BSBCA) that is utilized in protein cross-linking techniques.
  • Preparation of electrolyte solution to study the effect of electrolyte composition on the conversion of CO2 to CO by electrochemical reduction.
  • Preparation of CSK (cytoskeleton) buffer for the three-dimensional (3D) slide method of preserving the 3D chromatin structure of testicular germ cells.
  • Synthesis of ZSMs (zeolite socony mobils).
Sodium hydroxide may be employed for the deterimination of specific surface area of colloidal silica, via titration. It may be employed for the direct oxidation of sodium borohydride, which was investigated by cyclic and linear voltammetry, chronoamperometry and chronopotentiometry. It may be used to prepare citrate buffer and borate buffer. It may be used in the synthesis of :
  • alkylaryl amidosulfobetaines
  • (3 -[4-teroctylphenoxyethoxyethoxyethyl] dimethylammonio propane sulfonate (XOSB)
  • trisulfobetaines (TriSBn)


25, 500, 6×500 g in poly bottle
1, 2.5 kg in poly bottle
12, 25, 50 kg in poly drum

Información legal

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC



Palabra de señalización


Frases de peligro


Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A


8B - Non-combustible, corrosive hazardous materials

WGK Alemania


Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

The First Fluoride-Free Hiyama Reaction of Vinylsiloxanes Promoted by Sodium Hydroxide in Water.
Alacid E &amp; Najera C
Advanced Synthesis & Catalysis, 348(15), 2085-2091 (2006)
Effect of Cations on the Electrochemical Conversion of CO2 to CO.
Thorson MR, et al.
Journal of the Electrochemical Society, 160(1), F69-F74 (2013)
Selective oxidation of glycerol to glyceric acid using a gold catalyst in aqueous sodium hydroxide.
Carrettin S, et al.
Chemical Communications (Cambridge, England), 7, 696-697 (2002)
Satoshi H Namekawa
Journal of visualized experiments : JoVE, (83)(83), e50819-e50819 (2014-01-25)
During testicular germ cell differentiation, the structure of nuclear chromatin dynamically changes. The following describes a method designed to preserve the three-dimensional chromatin arrangement of testicular germ cells found in mice; this method has been termed as the three-dimensional (3D)...
Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development.
Krishnamurthy VV, et al.
Journal of Visualized Experiments, 124, e55823-e55823 (2017)

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