119R-1

Sigma-Aldrich

CD19 (EP169) Rabbit Monoclonal Primary Antibody

NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

500
100

forma del anticuerpo

culture supernatant

antibody product type

primary antibodies

clon

EP169, monoclonal

descripción

(For In Vitro Diagnostic Use in Select Regions (See Chart))

formulario

buffered aqueous solution

species reactivity

human

envase

vial of 0.1 mL concentrate (119R-14)
vial of 0.5 mL concentrate (119R-15)
bottle of 1.0 mL predilute (119R-17)
vial of 1.0 mL concentrate (119R-16)
bottle of 7.0 mL predilute (119R-18)

manufacturer/tradename

Cell Marque

aplicaciones

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotipo

IgG

conjugado

unconjugated

control

tonsil

enviado en

wet ice

temp. de almacenamiento

2-8°C

visualización

membranous

Categorías relacionadas

Descripción general

CD19 is present in both normal and malignant B-cells and has long been considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, mantle zone cells, and scattered cells in the interfollicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, CD19 is also expressed in immature B-cells; although recent studies have described CD19 loss in a few B-cell neoplasms.1-3

Calidad


IVD

IVD

IVD

RUO

Ligadura / enlace

CD19 Positive Control Slides, Product No. 119S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

RIDADR

NONH for all modes of transport

Certificado de Análisis
N Masir et al.
Histopathology, 48(3), 239-246 (2006-01-25)
To investigate whether an antibody against an intracellular epitope can detect CD19 in routine biopsy specimens and thus to document in detail its expression in human lymphomas. A polyclonal antibody to the C terminus of CD19 was used to immunostain...
Miho Kimura et al.
International journal of hematology, 85(1), 41-48 (2007-01-31)
To clarify the clinicopathologic significance of a loss of CD19 expression in diffuse large B-cell lymphoma (DLBCL), we evaluated CD19 expression immunohistochemically in frozen sections from 227 patients who had received diagnoses of DLBCL according to the World Health Organization...
S A Greenberg et al.
Neurology, 65(11), 1782-1787 (2005-12-14)
Previous immunohistochemical studies of muscle from patients with inclusion body myositis and polymyositis found many more T cells than B cells, suggesting a role for intramuscular cell-mediated immune mechanisms rather than humoral mechanisms. Microarray studies were performed on muscle biopsy...

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