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452M-9

Sigma-Aldrich

Cytokeratin (CAM 5.2) Mouse Monoclonal Antibody

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Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

CAM 5.2, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (452M-94)
vial of 0.5 mL concentrate (452M-95)
bottle of 1.0 mL predilute (452M-97)
vial of 1.0 mL concentrate (452M-96)
bottle of 7.0 mL predilute (452M-98)

fabricante / nombre comercial

Cell Marque™

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotipo

IgG2aκ

control

appendix, hepatocellular carcinoma

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Categorías relacionadas

Descripción general

Anti-CAM 5.2 is a mouse monoclonal antibody that was generated by using the human colorectal carcinoma cell line HT24. Anti-CAM 5.2 reacts with cytokeratins 7 and 8, which are expressed in simple and glandular epithelia and transitional epithelium. Anti-CAM 5.2 reacts with most normal epithelium and with most carcinomas, including those arising in the lung, liver, pancreas, GI tract, breast, genitourinary system, female reproductive organs, and some endocrine organs. This antibody can be used as an aid to identify epithelial differentiation in normal and neoplastic tissues.

Ligadura / enlace

Cytokeratin (CAM 5.2) Positive Control Slides, Product No. 452S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

control

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J H Sinard
Archives of ophthalmology (Chicago, Ill. : 1960), 117(6), 776-783 (1999-06-16)
Diagnosis of sebaceous carcinoma of the periorbital region is often delayed. Clinically, this lesion can mimic several inflammatory disorders. Histopathologically, it can mimic either squamous cell or basal cell carcinoma. To identify an immunohistochemical approach to assist in the diagnosis
Nelson G Ordóñez
Human pathology, 44(7), 1195-1215 (2013-02-23)
A relatively large number of broad-spectrum immunohistochemical epithelial markers that can be used as part of the screening panels employed in the recognition of the main cell lineages during the initial evaluation of a poorly differentiated tumor are currently available.
M M Cosgrove et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 6(3), 342-347 (1993-05-01)
In this study, 29 formalin-fixed, paraffin-embedded astrocytic tumors were analyzed immunocytochemically with the antikeratin monoclonal antibodies Mak-6 and Cam 5.2 and a polyclonal antibody against glial fibrillary acidic protein (GFAP). Immunoreactivity for Mak-6 was present in 29 cases (100%) including
Chin-Chen Pan et al.
Applied immunohistochemistry & molecular morphology : AIMM, 13(4), 347-352 (2005-11-11)
The differential diagnoses of hepatocellular carcinoma (HCC), renal cell carcinoma (RCC), and adrenocortical carcinoma (ACC) are sometimes difficult due to their overlapping histologic features. Immunohistochemistry is a helpful adjunct in supporting the histologic diagnosis. In this study, the authors used
Feiling Feng et al.
Oncotarget, 8(3), 5349-5360 (2016-12-29)
Gallbladder sarcomatoid carcinoma is a rare cancer with no clinical standard treatment. With the rapid development of next generation sequencing, it has been able to provide reasonable treatment options for patients based on genetic variations. However, most cancer drugs are

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