A1651

Adenosine 3′-phosphate 5′-phosphosulfate lithium salt hydrate

≥60%

• Synonym(s): 3′-Phosphoadenosine 5′-phosphosulfate lithium salt, APPS, Active sulfate, PAPS
• Empirical Formula (Hill Notation): C₁₀H₁₅N₅O₁₃P₂S · xLi⁺ · yH₂O
• CAS Number: 109434-21-1
• Molecular Weight: 507.26 (free acid basis)
• Beilstein: 8181191
• eCl@ss: 32160414
• NACRES: NA.51

Properties

• Nivel de calidad: 200
• ensayo: ≥60%
• formulario: powder
• enviado en: dry ice
• temp. de almacenamiento: −70°C
• InChI: 1S/C10H15N5O13P2S.4Li.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(27-29(17,18)19)4(26-10)1-25-30(20,21)28-31(22,23)24;;;;;/h2-4,6-7,10,16H,1H2,(H,20,21)(H2,11,12,13)(H2,17,18,19)(H,22,23,24);;;;;1H2/q;4*+1;/p-4/t4-,6-,7-,10-;;;;;/m1...../s1
• InChI key: UGODCLHJOJPPHP-AZGWGOJFSA-J

Description

Aplicación

3′-Phosphoadenosine 5′-phosphosulfate (PAPS) is used as a universal sulfonate donor for in vivo sulfonation by sulfotransferases. PAPS is used for the sulfation of glycans. PAPS is also useful to study the distribution and function of its biological transporter(s).

Adenosine 3′-phosphate 5′-phosphosulfate lithium salt has been used in a study that cloned and characterized a mammalian lithium-sensitive bisphosphate 3′-nucleotidase inhibited by inositol 1,4-bisphosphate. Adenosine 3′-phosphate 5′-phosphosulfate lithium salt has also been used in a study to assess the golgi-resident PAP-specific 3′-phosphatase-coupled sulfotransferase assays.

Calidad

Major impurities appear to be adenosine 3′,5′-diphosphate, sulfate and ammonia substitution products.

Precaución

Rapid decomposition occurs when exposed to room temperature: up to 17% per day at 37 °C. We ship on dry ice to minimize decomposition in transit.

Safety Information

• pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315 - H319 - H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 3
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves