IgM antibody is produced by B cells and plays a pivotal role in primary defence mechanism. The main function is to recognise and eliminate foreign invaders like bacteria and viruses, cellular waste as well as precancerous and cancerous lesions. Anti-human IgM (μ-chain specific) −biotin antibody can be used in micro ELISA to determine IgD isotype antibody to phosphorylcholine (PC) . Goat anti-human IgM antibodies react specifically with human IgM but not with other human immunoglobulins.
Human IgMs are the initial immunoglobulin isotypes that appear in blood in response to the first exposure to external antigens. IgMs have been implicated in CNS myelin repair and increased secretory IgM levels have been linked to rhino-conjunctivitis . Anti-Human IgM (μ-chain specific)-Biotin antibody is specific for human IgM and does not bind other human immunoglobulins.
Purified human IgM.
Purified human IgM
Anti-Human IgM (μ-chain specific)-Biotin antibody is suitable for use in ELISA (1:2000) .
2 mL in glass bottle
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide
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