Merck
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D5670

Sigma-Aldrich

Sodium deoxycholate monohydrate

BioXtra, ≥99.0% (titration)

Sinónimos:
Desoxycholic acid sodium salt, 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO4 · H2O
Número de CAS:
Peso molecular:
432.57
Beilstein:
3643164
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.25

descripción

anionic

línea de producto

BioXtra

ensayo

≥99.0% (titration)

formulario

powder

actividad óptica

[α]20/D +44±2° in H2O(lit.)

mol peso

432.57 g/mol

technique(s)

electrophoresis: suitable
immunoprecipitation (IP): suitable

impurezas

Insoluble matter, passes filter test
≤0.5% Cholic acid

pH

7.5-9.5 (20 °C, 0.1 M in H2O)

solubilidad

H2O: 0.1 M, clear, colorless

trazas de anión

sulfate (SO42-): ≤0.02%

trazas de catión

Al: ≤0.002%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.05%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.010%
Li: ≤0.0005%
Mg: ≤0.002%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.002%
Zn: ≤0.0005%

absorción

≤0.08 at 280 in H2O at 0.1 M
≤0.10 at 260 in H2O at 0.1 M

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3CCC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O4.Na.H2O/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);;1H2/q;+1;/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;;/m1../s1

InChI key

NDVHNZISGVSFMP-WTCAICSISA-M

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Descripción general

Sodium deoxycholate (SDC) monohydrate is a bile acid salt.

Aplicación

Sodium deoxycholate monohydrate has been used in a study to assess a method for the immobilization of lipoxygenase in an alginate-silicate gel matrix. It has also been used in a study to investigate the in vitro dissolution of gall stones.
Powerful solubilization agent; used in the solubilization of estrogen synthetase from human placental microsomes.

Envase

5, 25 g in poly bottle

Acciones bioquímicas o fisiológicas

Bile Salt

pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

Effect of various lipid-bile salt mixed micelles on the intestinal absorption of amphotericin-B in rat
Dangi, J., et al.
Drug Devel. Ind. Pharm., 24, 631-631 (1998)
R P Modi et al.
Journal of the Indian Medical Association, 89(5), 129-132 (1991-05-01)
An in vitro study on dissolution of 36 gall-stones obtained from 3 patients (12 stones from each patient) was carried out in heparin, bile salt and clofibrate solutions of different strengths. Heparin was found to be a poor solvent while
Liquid crystals and phase equilibria binary bile salt-water systems.
Marques EF, et al.
Langmuir, 16(11), 5178-5186 (2000)
Immobilization of lipoxygenase in an alginate-silicate solgel matrix: formation of fatty acid hydroperoxides
Hsu, A., et al.
Biotechnology Letters, 19, 71-71 (1997)
Suguru Yamasaki et al.
Scientific reports, 9(1), 177-177 (2019-01-19)
During infection, Salmonella senses and responds to harsh environments within the host. Persistence in a bile-rich environment is important for Salmonella to infect the small intestine or gallbladder and the multidrug efflux system AcrAB-TolC is required for bile resistance. The

Artículos

Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine.

Probiotics and Human Health

Today, diverse studies report the benefits of probiotics, such as inhibitory effects on pathogens, aid in the management or prevention of chronic intestinal inflammatory diseases or atopic syndromes, and support to the immune system. Potential beneficial applications abound, researchers continue to evaluate the effictiveness and clarify the mechanisms of action of probiotics.

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