Merck
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G2904

Sigma-Aldrich

Monoclonal Anti-Goat/Sheep IgG antibody produced in mouse

clone GT-34, ascites fluid

Sinónimos:
Monoclonal Anti-Goat/Sheep IgG

origen biológico

mouse

conjugado

unconjugated

forma del anticuerpo

ascites fluid

antibody product type

secondary antibodies

clon

GT-34, monoclonal

contiene

15 mM sodium azide

species reactivity

bovine, sheep, goat

should not react with

rat, chicken, mouse, horse, feline, pig, canine, guinea pig, rabbit, human

technique(s)

indirect ELISA: 1:10,000-1:20,000

isotipo

IgG1

enviado en

dry ice

temp. de almacenamiento

−20°C

Descripción general

IgG is the main type of antibody in human serum, secreted by the B cells. It is found in blood. IgG consists of four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, which are linked by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4.
The antibody reacts with an epitope located on the heavy chain of goat IgG1 and IgG2.

Especificidad

Monoclonal Anti-Goat/Sheep IgG recognizes an epitope located on the heavy chain of goat IgG1 and IgG2. The antibody shows strong cross-reactivity with sheep IgG and weak cross-reactivity with bovine IgG. No cross-reactivity is observed with IgG derived from human, guinea pig, rat, horse, dog, chicken, pig, mouse, rabbit, or cat.

Aplicación

Monoclonal Anti-Goat/Sheep IgG antibody produced in mouse has been used in:
  • enzyme linked immunosorbent assay (ELISA)
  • immunoblotting
  • immunoprecipitation
  • immunoelectrophoresis

Acciones bioquímicas o fisiológicas

IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.

Forma física

The product is provided as ascites fluid with 0.1% sodium azide as preservative.

Almacenamiento y estabilidad

For continuous use, store at 2–8 °C for up to one month. For extended storage, solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

nwg

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Introduzca el número de lote para buscar un certificado de análisis (COA).

Certificado de origen

Introduzca el número de lote para buscar un Certificado de origen (COO).

Quotes and Ordering

Seasonal variations of phagocytic response, immunoglobulin G (IgG) and plasma cortisol levels in Dhofari goats
Al-Busaidi R, et al.
Small Ruminant Research, 79(2-3), 118-123 (2008)
Tom N McNeilly et al.
Veterinary research, 44, 70-70 (2013-08-24)
Teladorsagia circumcincta is an important pathogenic nematode of sheep. It has been demonstrated previously that stimulation of murine T lymphocytes with excretory-secretory (ES) products derived from fourth stage larvae of T. circumcincta (Tci-L4-ES) results in de novo expression of Foxp3
Guillaume Sallé et al.
International journal for parasitology, 48(5), 395-402 (2018-03-15)
Some nematode species are economically important parasites of livestock, while others are important human pathogens causing some of the most important neglected tropical diseases. In both humans and animals, anthelmintic drug administration is the main control strategy, but the emergence
A revised nomenclature for allergy: an EAACI position statement from the EAACI nomenclature task force
Johansson SGO, et al.
Allergy, 56(9), 813-824 (2001)
Mohammad H El-Dakdouki et al.
Pharmaceutical research, 31(6), 1426-1437 (2013-04-10)
The cell surface adhesion molecule CD44 plays important roles in the initiation and development of atherosclerotic plaques. We aim to develop nanoparticles that can selectively target CD44 for the non-invasive detection of atherosclerotic plaques by magnetic resonance imaging. Magnetic glyconanoparticles

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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