G5417

Glycine

• Synonym(s): Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Linear Formula: NH₂CH₂COOH
• CAS Number: 56-40-6
• Molecular Weight: 75.07
• Beilstein: 635782
• Número de EC: 200-272-2
• Número MDL: MFCD00008131
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 24895210
• NACRES: NA.25

Properties

• origen biológico: non-animal source
• Nivel de calidad: 400
• ensayo: ≥98.5%
• formulario: crystalline powder
• manufacturer/tradename: Ajinomoto
• technique(s): cell culture | mammalian: suitable
• impurezas: endotoxin, heavy metals, trace metals, residual solvents, tested
• pH: 5.9-6.4
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• solubilidad: H₂O: 100 mg/mL
• Absorción UV: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: -0.006; λ: 280 nm A_max: ≤0.04; λ: 280 nm A_max: -0.003
• idoneidad: suitable for manufacturing use
• application(s): pharmaceutical (small molecule)
• actividad extraña: cytotoxicity, tested
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Gene Information: rat ... Grin2a(24409)

Description

Descripción general

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Aplicación

Glycine is a non-essential amino acid. It is the simplest of the amino acids and plays various roles in biology. It is structurally unique among the biological amino acids in that it does not have an asymmetric center, and thus is not chiral. It is commonly used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Acciones bioquímicas o fisiológicas

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Safety Information

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• WGK: WGK 1
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)