G7403

Glicina

≥99% (titration), suitable for electron microscopy, BioXtra

• Sinónimos: Glicocola, Ácido aminoacético, Ácido aminoetanoico
• Fórmula lineal: NH₂CH₂COOH
• CAS Number: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número CE: 200-272-2
• Número MDL: MFCD00008131
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 24895306
• NACRES: NA.26

Propiedades

• Product Name: Glicina, BioXtra, ≥99% (titration)
• Línea del producto: BioXtra
• Nivel de calidad: 200
• Ensayo: ≥99% (titration)
• Formulario: powder
• técnicas: electron microscopy: suitable
• impurezas: Insoluble matter, passes filter test
• residuo de ign.: ≤0.05%
• pérdida: ≤0.05% loss on drying, HV, 20-26 °C
• color: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• solubilidad: 1 M HCl: 1 M, clear, colorless
• trazas de anión: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• trazas de catión: Al: ≤0.0005%; As: ≤0.00001%; Ba: ≤0.0005%; Bi: ≤0.0005%; Ca: ≤0.001%; Cd: ≤0.0005%; Co: ≤0.0005%; Cr: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Li: ≤0.0005%; Mg: ≤0.0005%; Mn: ≤0.0005%; Mo: ≤0.0005%; NH₄⁺: ≤0.02%; Na: ≤0.02%; Ni: ≤0.0005%; Pb: ≤0.0005%; Sr: ≤0.0005%; Zn: ≤0.0005%
• Absorción: ≤0.04 at 260 in 1 M HCl at 1 M; ≤0.04 at 280 in 1 M HCl at 1 M
• cadena SMILES: NCC(O)=O
• Absorción UV: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: 0.003; λ: 260 nm A_max: 0.006
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Clave InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Información sobre el gen: rat ... Grin2a(24409)

Descripción

Aplicación

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope.[1] It has also been used for sample fixation in the process of immunolabeling.[2]

Acciones bioquímicas o fisiológicas

Glycine is a non-essential amino acid.[3] Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors.[4] Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.[3]

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)