G8769

Sigma-Aldrich

D-(+)-Glucose solution

45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

Empirical Formula (Hill Notation):
C6H12O6
Número de CAS:
Peso molecular:
180.16
Beilstein/REAXYS Number:
1281608
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.75

Nivel de calidad

200

esterilidad

sterile-filtered

línea de producto

BioXtra

formulario

solution

concentración

45% in H2O

aplicaciones

cell culture | mammalian: suitable

impurezas

endotoxin, tested

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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Descripción general

Glucose is the energy currency essential for physiological processes in the living cells. It serves as a precursor for glycoproteins, glycolipids and glycosaminoglycans.

Aplicación

D-(+)-Glucose solution has been used as a medium supplement:
  • in Dulbecco′s Modified Eagle Medium (DMEM) for culturing Flp-In  293 cells
  • in dissection medium for coronal slices from rat brain
  • in neurobasal medium for culturing hippocampi cells

Provides the primary energy source for cell metabolism.

Acciones bioquímicas o fisiológicas

Glucose is a crucial component for the growth and maintenance of mammalian cells in in vitro conditions and is essential for productivity and quality. Its high metabolic turnover favors osteoclast differentiation. The levels of glucose modulate the migration and growth of tumor cells. HeLa cells display high mobility at low glucose levels.

storage_class_code

10 - Combustible liquids

WGK Alemania

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

Investigation of the Influence of Glucose Concentration on Cancer Cells by Using a Microfluidic Gradient Generator without the Induction of Large Shear Stress
Ishida T, et al.
Micromachines, 7(9), 155-155 (2016)
Chad A Dumstorf et al.
Molecular cancer therapeutics, 9(12), 3158-3163 (2010-10-26)
Enzastaurin (LY317615.HCl) is currently in a phase III registration trial for diffuse large B-Cell lymphoma and numerous phase II clinical trials. Enzastaurin suppresses angiogenesis and induces apoptosis in multiple human tumor cell lines by inhibiting protein kinase C (PKC) and...
Protein kinase C activation causes neurite retraction via cyclin D 1 and p60-katanin increase in rat hippocampal neurons
Korulu S, et al.
The European Journal of Neuroscience, 37(10), 1610-1619 (2013)
An ex vivo method for evaluating the biocompatibility of neural electrodes in rat brain slice cultures
Koeneman BA, et al.
Journal of Neuroscience Methods, 137(2), 257-263 (2004)
High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat culture of CHO cells
Vergara M, et al.
Testing, 13(8), e0202098-e0202098 (2018)
Artículos
Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.
Más información

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