GW21034

Anti-Interleukin-21 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-IL-21
• Número MDL: MFCD03455324
• NACRES: NA.41

Properties

• origen biológico: chicken
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• antibody product type: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• species reactivity: human
• manufacturer/tradename: Genway 15-288-21034
• technique(s): indirect ELISA: suitable; western blot: suitable
• Nº de acceso NCBI: AAH69124.1
• Nº de acceso UniProt: Q9HBE4
• enviado en: wet ice
• temp. de almacenamiento: −20°C
• Gene Information: human ... IL21(59067)

Description

Inmunógeno

Immunogen Sequence: GI # 46575632, sequence 33-111

Recombinant interleukin 21

Aplicación

Anti-Interleukin-21 antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Acciones bioquímicas o fisiológicas

Interleukin-21 (IL-21) is a protein encoded by the IL21 gene in humans. It is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells. Cytokines are crutial for the regulation of haematopoiesis and immune responses. It can influence lymphocyte development. IL21 has an important role in the proliferation and maturation of natural killer (NK) cell populations from bone marrow. The gene may play a role in the development of Systemic lupus erythematosus (SLE). IL-21 is essential for B cell activation, expansion and PC differentiation induced by direct interaction of B cells with activated T cells. Polymorphisms of this gene is associated with several cancers.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• WGK: WGK 1
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)