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GW21465

Sigma-Aldrich

Anti-PTPRC antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):
Anti-Leukocyte common antigen, Anti-LCA, Anti-CD45
NACRES:
NA.41

origen biológico

chicken

Nivel de calidad

200

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

antibody product type

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

species reactivity

human

manufacturer/tradename

Genway 15-288-21465

technique(s)

western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

human ... PTPRC(5788)

Inmunógeno

Immunogen Sequence: GI # 18641347, sequence 482-552
Recombinant protein tyrosine phosphatase, receptor type, C isoform 1

Aplicación

Anti-PTPRC antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Acciones bioquímicas o fisiológicas

Protein tyrosine phosphatase, receptor type, C is an enzyme encoded by the PTPRC gene in humans. It is also known as CD45 antigen (CD stands for cluster of differentiation) and is originally called leukocyte common antigen (LCA). PTPRC acts as a binding receptor for galectin-3 and helps in inducing apoptosis of Jurkat cells. It plays a novel role on innate immune cells in promoting lymphopenia-induced T cell proliferation. The leukocyte-specific tyrosine phosphatase impacts T cell development and activation by modulating TCR signaling.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificate of Analysis

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Certificate of Origin

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SDS

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