Merck

I5131

Sigma-Aldrich

IgG from sheep serum

reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

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Sinónimos:
Sheep IgG
Número MDL:
NACRES:
NA.46

origen biológico

sheep

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

purified immunoglobulin

grado

reagent grade

Análisis

≥95% (SDS-PAGE)

formulario

essentially salt-free, lyophilized powder

isotipo

IgG

solubilidad

saline: 1 mg/mL at -20 °C (Repeated freezing and thawing is not recommended.)

temp. de almacenamiento

2-8°C

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Este artículo
I8265I5006I5381
IgG from sheep serum reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

Sigma-Aldrich

I5131

IgG from sheep serum

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I8265

IgG from sheep serum

IgG from rabbit serum reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

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I5006

IgG from rabbit serum

Sigma-Aldrich

Sigma-Aldrich

I5381

IgG from mouse serum

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody form

-

antibody form

-

antibody form

-

form

essentially salt-free, lyophilized powder

form

buffered aqueous solution

form

essentially salt-free, lyophilized powder

form

lyophilized powder

isotype

IgG

isotype

-

isotype

-

isotype

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

Descripción general

IgG consists of four isotypes IgG1, IgG2, IgG3 and IgG4. It contains four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, which are connected by inter-chain disulfide bonds.

Aplicación

Purified IgG may be used as a reference antigen, standard, blocking agent or coating protein in a variety of immunoassays including ELISA, dot immunobinding, Western immunoblotting, immunodiffusion, immunoprecipitation and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solid-phase immunoadsorbents.

Acciones bioquímicas o fisiológicas

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
IgG mediates transplacental transport and participates in the secondary immune response. IgG activates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a key role in antibody dependent cell-mediated cytotoxicity (ADCC) and phagocytosis. It might be linked to allergy. It has the longest serum half life.

Nota de análisis

Protein concentration should be determined after reconstitution by absorbance at 280 nm (E1%/280 = 14).

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Las referencias de los producto se combinan con los tamaños de envase y las cantidades cuando se muestran en la página web, por ejemplo: T1503-25G. Asegúrese de introducir el número de producto ÚNICAMENTE en el campo del Número de producto (ejemplo: T1503).

Ejemplo

T1503
Referencia del producto
-
25G
Tamaño del envase/cantidad

Otros ejemplos

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

introducir como 1.000309185)

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Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch».

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