I8907

Interferon β from rat

≥95%, recombinant, expressed in CHO cells, lyophilized powder, suitable for cell culture

• Sinónimos: IFN-β
• Número MDL: MFCD04040885
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• origen biológico: rat
• Nivel de calidad: 200
• recombinante: expressed in CHO cells
• Ensayo: ≥95%
• Formulario: lyophilized powder
• mol peso: ~20 kDa
• envase: pkg of 1 vial
• concentración: ≥100000 units/mL
• técnicas: cell culture | mammalian: suitable
• Nº de acceso UniProt: P70499
• Condiciones de envío: dry ice
• temp. de almacenamiento: −70°C
• Información sobre el gen: rat ... Ifnb1(24481)

Descripción

Acciones bioquímicas o fisiológicas

Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities.

Interferon β belongs to the type 1 interferon family pf proteins.[1] It is also needed for the inhibition of tumor cell growth via cell death, S-phase increase and mediating differentiation.[2] It is also important for bone homeostasis.[3]

Forma física

Lyophilized from phosphate buffered saline (PBS) containing 125 mM trehalose.

Nota de análisis

The biological activity is determined in the cytopathic effect inhibition assay using rat epithelial-like (RATEC) cells with vesicular stomatitis virus (VSV). The cytopathic effect of 50% is produced with approximately 1 unit/ml interferon. Since there is no international rat interferon β standard, units are determined with respect to the NIH international standard reference for mouse interferon α/β.

Información de seguridad

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)