M1398

IgG1, Kappa from murine myeloma

clone MOPC 31C, ascites fluid, lyophilized powder

• Sinónimos: Mouse IgG1-κ
• Número MDL: MFCD00164798
• Código UNSPSC: 12352203
• NACRES: NA.46

Propiedades

• origen biológico: mouse
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: ascites fluid
• clon: MOPC 31C, monoclonal
• Formulario: lyophilized powder
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified

Descripción

Descripción general

The MOPC 31C tumor line that produces mouse IgG1,k is a mineral oil-induced plasmacytoma originated and carried subcutaneously in BALB/c mice. Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody.[1] An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense.[2] It is a glycoprotein. IgG is a major class of immunoglobulin.[3] Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.[3] Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.[4]

Aplicación

IgG1, Kappa from murine myeloma has been used in immunohistochemistry.[5]

Acciones bioquímicas o fisiológicas

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.[6]

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions.[7] IgG2a has cytotropic properties and IgG2 molecules have the ability to activate the complement system.[3] IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.[4]

Reconstitución

Reconstitute with 1 ml deionized water.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)