M6020

Sigma-Aldrich

D-(+)-Mannose

powder, BioReagent, suitable for cell culture

Sinónimos:
D-Mannopyranose
Empirical Formula (Hill Notation):
C6H12O6
Número de CAS:
Peso molecular:
180.16
Beilstein/REAXYS Number:
1564373
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.75

origen biológico

plant (Spruce, Birch or Beech Wood, Glucose)

Nivel de calidad

200

línea de producto

BioReagent

ensayo

≥99%

formulario

powder

aplicaciones

cell culture | mammalian: suitable

mp

133-140 °C (lit.)

solubilidad

H2O: 50 mg/mL

Industria destacada

Agriculture

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

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Descripción general

Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.

Aplicación

D-(+)-Mannose has been used:
  • as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
  • as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
  • in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines

Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.

Envase

25, 100, 500 g in poly bottle

Acciones bioquímicas o fisiológicas

Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.

storage_class_code

13 - Non Combustible Solids

WGK Alemania

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificado de Análisis

Certificado de origen

M J Carlino et al.
Gut microbes, 12(1), 1-21 (2020-11-03)
Infectious diarrhea causes approximately 179 million illnesses annually in the US. Multiplex PCR assays for enteric pathogens detect enteropathogenic Escherichia coli (EPEC) in 12-29% of diarrheal stool samples from all age groups in developed nations. The aim of this study...
Golgi glycosylation
Stanley P
Cold Spring Harbor Perspectives in Biology, 3(4), a005199-a005199 (2011)
Essentials of Carbohydrate Chemistry by John F. Robyt
Pendarvis R
The Chemical Educator, 3(5), 1-2 (1998)
Agrobacterium-mediated transformation of Sorghum bicolor using immature embryos
Transgenic Plants, 109-122 (2012)
Metabolic manipulation of glycosylation disorders in humans and animal models
Freeze HH and Sharma V
Seminars in Cell & Developmental Biology, 21(6), 655-662 (2010)

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