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Anti-Bcl-2 (ab1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Anti-B-cell CLL/lymphoma 2
Número MDL:

origen biológico


Nivel de calidad




forma del anticuerpo

affinity isolated antibody

antibody product type

primary antibodies




buffered aqueous solution

species reactivity

mouse, human


immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Nº de acceso UniProt

enviado en

dry ice

temp. de almacenamiento


Gene Information

human ... BCL2(596)

Descripción general

B-cell lymphoma 2 (BCL2), a proto-oncogene is made of three exons. It is widely expressed in immature B-cells and memory B cells. BCL2 is found at high levels in the thymus, spleen, and lymph nodes. BCL2 gene is mapped to human chromosome 18q21.33.


a peptide corresponding to 15 amino acids near the N-terminus of human Bcl-2.


Anti-Bcl-2 (ab1) antibody produced in rabbit has been used in western blotting (1:100) (1:1000), immunohistochemistry (1:50), immunoprecipitation (IP) (1:1000)

Acciones bioquímicas o fisiológicas

B-cell lymphoma 2 (BCL2) plays a key role in maintaining the integrity of the mitochondrial membrane. It blocks the release of cytochrome C and its binding to apoptosis activating factor-1 (APAF1). BCL2 family proteins participate in modulating cell death. It also regulates apoptosis, necrosis, and autophagy. Upregulation of BCL2 is seen in several human cancers. Overexpression of BCL2 is observed in chronic lymphocytic leukemia (CLL), marginal cell lymphoma, and mantle cell lymphoma.

Ligadura / enlace

The action of this antibody can be blocked using blocking peptide SBP3335.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids



Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

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