Merck
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SAB1305503

Sigma-Aldrich

MONOCLONAL ANTI-CD25 antibody produced in mouse

clone 7G7B6, crude ascites, buffered aqueous solution

Synonym(s):
TAC antigen, IL2RA, p55, CD_antigen=CD25, Interleukin-2 receptor subunit alpha
NACRES:
NA.41

Nivel de calidad

100

origen biológico

mouse

forma del anticuerpo

crude ascites

antibody product type

primary antibodies

clon

7G7B6, monoclonal

formulario

buffered aqueous solution

mol peso

30819 Da

species reactivity

human

technique(s)

western blot: 1:100-~1:800

isotipo

IgG2a

Nº de acceso NCBI

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

human ... IL2RA(3559)

Descripción general

The CD25 gene, also referred to as IL2RA (interleukin 2 receptor subunit α), is mapped to human chromosome 10p15. The gene spans a length of 48 kb with eight exons.

Acciones bioquímicas o fisiológicas

The interleukin 2 receptor subunit α (IL2RA) gene encodes the α-chain of the IL-2 receptor complex. This receptor complex, made up of α, β, and a common γ chain, binds to its ligand, IL-2, which is a crucial growth factor for T- and B-cells. This ligand-receptor complex plays an important role in the regulation of immune responses. Variation in the chromosomal region containing this gene is associated with type 1 diabetes. This region is also linked to autoimmune thyroid disease indicating its role in autoimmunity. IL2RA has been found to confer a risk for multiple sclerosis.

Forma física

Supplied in PBS with 0.09% (W/V) sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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