SAB3300090

Sigma-Aldrich

Monoclonal Anti-GATA4 antibody produced in mouse

clone 9F9, purified immunoglobulin, buffered aqueous glycerol solution

Sinónimos:
Anti-MGC126629

origen biológico

mouse

forma del anticuerpo

purified immunoglobulin

antibody product type

primary antibodies

clon

9F9, monoclonal

formulario

buffered aqueous glycerol solution

mol peso

antigen 44.4 kDa

species reactivity

human

aplicaciones

immunohistochemistry: suitable
indirect immunofluorescence: suitable
western blot: suitable

isotipo

IgG3

conjugado

unconjugated

Nº de acceso NCBI

Nº de acceso UniProt

enviado en

dry ice

temp. de almacenamiento

−20°C

Gene Information

human ... GATA4(2626)

Inmunógeno

Recombinant fragment expressed in E. coli corresponding to amino acids 296-442of human GATA4

Descripción de destino

GATA4 encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.

Forma física

Solution in phosphate buffered saline containing 1% bovine serum albumin, 50% glycerol, and 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificado de Análisis

Certificado de origen

Chaitali Misra et al.
Human molecular genetics, 23(19), 5025-5035 (2014-05-27)
Mutations in GATA4 and TBX5 are associated with congenital heart defects in humans. Interaction between GATA4 and TBX5 is important for normal cardiac septation, but the underlying molecular mechanisms are not well understood. Here, we show that Gata4 and Tbx5...

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