SAB3500285

Anti-LAMP-1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-Lysosome associated membrane protein 1
• Número MDL: MFCD01864611
• NACRES: NA.41

Properties

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• antibody product type: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: predicted mol wt 46 kDa
• species reactivity: rat, human, mouse
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Nº de acceso NCBI: NP_005552
• Nº de acceso UniProt: P11279
• enviado en: dry ice
• temp. de almacenamiento: −20°C
• Gene Information: human ... LAMP1(3916)

Description

Descripción general

Lysosomal-associated membrane protein 1 (LAMP-1) is a type I transmembrane protein with a short cytoplasmic tail containing a lysosome-targeting signal. The gene encoding this protein is localized on human chromosome 13q34.

Inmunógeno

LAMP-1 antibody was raised against a 15 amino acid peptide from near the center of human LAMP-1.

Aplicación

Anti-LAMP-1 antibody produced in rabbit has been used in Western blotting.

Acciones bioquímicas o fisiológicas

Lysosomal-associated membrane protein 1 (LAMP-1) functions as an intracellular receptor. It is found to be expressed in the cytoplasm of several types of tumor cells and may be involved in tumor invasion. LAMP-1 is essential for perforin trafficking to the lytic granules and motility of these lytic granules. Knockdown of this protein leads to inhibition of cytotoxicity of human natural killer cells.

Características y beneficios

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Ligadura / enlace

The action of this antibody can be blocked using blocking peptide SBP3500285.

Forma física

Supplied in PBS with 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• WGK: WGK 2