Merck
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SAB4700135

Sigma-Aldrich

Monoclonal Anti-CD28 antibody produced in mouse

low endotoxin, clone CD28.2, purified immunoglobulin, buffered aqueous solution

NACRES:
NA.41

Nivel de calidad

100

origen biológico

mouse

conjugado

unconjugated

forma del anticuerpo

purified immunoglobulin

antibody product type

primary antibodies

clon

CD28.2, monoclonal

formulario

buffered aqueous solution

species reactivity

nonhuman primates, human

concentración

1 mg/mL

technique(s)

flow cytometry: suitable

isotipo

IgG1

Nº de acceso NCBI

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

2-8°C

Gene Information

human ... CD28(940)

Descripción general

Cluster of differentiation 28 (CD28) antigen is a co-stimulatory receptor expressed in naive T-cells.[52} It contains a short cytoplasmic tail and two proline-rich motifs. CD28 is encoded by the gene mapped to human chromosome 2q33.2.

Inmunógeno

DC28.1.3.3 hybridoma cells

Aplicación

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Acciones bioquímicas o fisiológicas

Cluster of differentiation 28 (CD28) antigen has a role in T-cell activation, proliferation, survival and function. It modulates thymic development, peripheral homeostasis and the suppressive functions of regulatory T cells. CD28 has a role in signal transduction and is involved in activating many adaptor proteins. Mutation in the gene increases the risk of susceptibility to rheumatoid arthritis.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in azide free phosphate buffered saline, pH 7.4; 0.2 um filter sterilized. Endotoxin level is less than 10 EU/mg of the protein, as determined by the LAL test.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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