Merck
  • SML0422
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SML0422

Sigma-Aldrich

Istradefylline

≥98% (HPLC)

Synonym(s):
(E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine, 8-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione, KW-6002
Empirical Formula (Hill Notation):
C20H24N4O4
CAS Number:
Molecular Weight:
384.43
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

Análisis

≥98% (HPLC)

formulario

powder

color

white to beige

solubilidad

DMSO: 5 mg/mL (clear solution)

temp. de almacenamiento

2-8°C

SMILES string

CCN1C(=O)N(CC)c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2C1=O

InChI

1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)15(12-13)28-5/h8-12H,6-7H2,1-5H3/b11-9+

InChI key

IQVRBWUUXZMOPW-PKNBQFBNSA-N

Gene Information

human ... ADORA2A(135)

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Istradefylline ≥98% (HPLC)

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Idalopirdine

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

color

white to beige

color

-

color

white to beige

color

white to beige

solubility

DMSO: 5 mg/mL (clear solution)

solubility

methanol: 50 mg/mL, clear to slightly hazy

solubility

DMSO: >20 mg/mL

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

-10 to -25°C

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

Acciones bioquímicas o fisiológicas

Istradefylline (KW-6002) is a potent and selective adenosine A2A receptor selective antagonist which has been investigated for use in Parkinson′s Disease.

Características y beneficios

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictogramas

Skull and crossbones

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Acute Tox. 3 Oral

Código de clase de almacenamiento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable


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