T0625

Sigma-Aldrich

Taurine

≥99%

Sinónimos:
2-Aminoethanesulfonic acid
Fórmula lineal:
NH2CH2CH2SO3H
Número de CAS:
Peso molecular:
125.15
Beilstein/REAXYS Number:
1751215
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.32

Nivel de calidad

200

origen biológico

synthetic

ensayo

≥99%

formulario

powder

aplicaciones

cell analysis: suitable

color

white

mp

>300 °C (lit.)

temp. de almacenamiento

room temp

SMILES string

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

Gene Information

human ... GRIN1(2902)
rat ... Ppm1a(24666)

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Categorías relacionadas

Descripción general

Taurine (2-aminoethanesulphonic acid) is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys.

Aplicación

Taurine has been used for the isolation and growth of taurine-utilizing purple non-sulfur bacteria and in phototrophic growth experiments.

Envase

10 mg in poly bottle
1 kg in poly bottle
10, 25, 100, 500 g in poly bottle

Acciones bioquímicas o fisiológicas

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Taurine modulates the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. It also has a role in bile formation and fat digestion. Deficiency of taurine is associated with anxiety, hyperactivity, epilepsy and depression.

Características y beneficios

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Información legal

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

storage_class_code

13 - Non Combustible Solids

WGK Alemania

WGK 2

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificado de Análisis

Certificado de origen

Phototrophic utilization of taurine by the purple nonsulfur bacteria Rhodopseudomonas palustris and Rhodobacter sphaeroides.
Novak RT
Microbiology, 150(Pt 6), 1881-1891 (2004)
The potential health benefits of taurine in cardiovascular disease.
Xu YJ
Experimental and Clinical Cardiology, 13(2), 57-65 (2008)
Deniz Tasdemir et al.
Bioorganic & medicinal chemistry, 15(21), 6834-6845 (2007-09-04)
The type II fatty acid pathway (FAS-II) is a validated target for antimicrobial drug discovery. An activity-guided isolation procedure based on Plasmodium falciparum enoyl-ACP reductase (PfFabI) enzyme inhibition assay on the n-hexane-, the CHCl(3-) and the aq MeOH extracts of...
Felizia K Voss et al.
Science (New York, N.Y.), 344(6184), 634-638 (2014-05-03)
Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion channel VRAC, has remained unknown. A genome-wide small interfering RNA screen in mammalian cells identified LRRC8A as...
Zi-Bing Jin et al.
PloS one, 6(2), e17084-e17084 (2011-02-25)
Retinitis pigmentosa (RP) is the most common inherited human eye disease resulting in night blindness and visual defects. It is well known that the disease is caused by rod photoreceptor degeneration; however, it remains incurable, due to the unavailability of...

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