Merck
All Photos(5)

T1147

Sigma-Aldrich

apo-Transferrin human

powder, BioReagent, suitable for cell culture, ≥98% (agarose gel electrophoresis)

Synonym(s):
Human transferrin, Siderophilin
CAS Number:
Número de EC:
Número MDL:
NACRES:
NA.75

Nivel de calidad

200

origen biológico

human plasma

línea de producto

BioReagent

ensayo

≥98% (agarose gel electrophoresis)

formulario

powder

mol peso

76-81 kDa

concentración

~25 mM

technique(s)

cell culture | mammalian: suitable

impurezas

HIV and HBsAg, source material tested negative
≤0.005% iron

solubilidad

H2O: 50 mg/mL

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

human ... TF(7018)

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Aplicación

Apo-Transferrin human can be supplemented with iron or used to bind free iron present in media. It is also used to transport iron into mammalian cells.

Envase

100, 5×100, 500 mg in poly bottle
1, 5 g in poly bottle

Acciones bioquímicas o fisiológicas

Transferrin is the primary iron binding and cell delivery molecule present in serum. Serum-free cell culture systems require a delivery format for iron. Transferrin is the preferential delivery form of iron because cells process transferrin bound iron in a physiologically appropriate way through transferrin receptors on the cell surface. Human apo-transferrin is a high affinity transferrin that can be used with a wide range of cells types. Apo-transferrin can be loaded with iron prior to use or added directly to an iron containing medium.

Otras notas

Non-heme iron-transport protein.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Certificate of Analysis

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Certificate of Origin

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Product Information Sheet

Quotes and Ordering

Articles

Transferrin in Cell Culture

How transferrin and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of transferrin.

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