Merck
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T3258

Sigma-Aldrich

Tetracycline

98.0-102.0% (HPLC)

Empirical Formula (Hill Notation):
C22H24N2O8 · xH2O
CAS Number:
Molecular Weight:
444.43 (anhydrous basis)
Beilstein:
2230417
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.85

Nivel de calidad

200

ensayo

98.0-102.0% (HPLC)

formulario

powder or crystals

condiciones de almacenamiento

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

color

faint yellow to dark yellow

espectro de actividad antibiótica

Gram-negative bacteria
Gram-positive bacteria

Modo de acción

protein synthesis | interferes

temp. de almacenamiento

2-8°C

SMILES string

CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

InChI

1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1

InChI key

OFVLGDICTFRJMM-WESIUVDSSA-N

Gene Information

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Descripción general

Chemical structure: tetracycline

Envase

5, 25 g in poly bottle

Acciones bioquímicas o fisiológicas

Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells. The inhibitory effects can be reversed by washing, suggesting that it is the reversibly bound antibiotic, and not the irreversibly bound drug, that is responsible for antibacterial action.

Mode of Resistance: The effects are inactivated via a loss of cell wall permeability.

Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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