Merck
  • Z0153
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Z0153

Sigma-Aldrich

ZM 241385

≥98% (HPLC)

Synonym(s):
4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol
Empirical Formula (Hill Notation):
C16H15N7O2
CAS Number:
Molecular Weight:
337.34
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

Análisis

≥98% (HPLC)

formulario

powder

color

white to tan

solubilidad

DMSO: >15 mg/mL

temp. de almacenamiento

room temp

SMILES string

Nc1nc(NCCc2ccc(O)cc2)nc3nc(nn13)-c4ccco4

InChI

1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)

InChI key

PWTBZOIUWZOPFT-UHFFFAOYSA-N

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assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

color

white to tan

color

white to beige

color

white to beige

color

white to tan

solubility

DMSO: >15 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: ≥5 mg/mL (warmed to 60° C)

storage temp.

room temp

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

Acciones bioquímicas o fisiológicas

ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.

Características y beneficios

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable


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