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Göknur Kalkan et al.
Cutaneous and ocular toxicology, 33(2), 109-114 (2013-07-12)
The conflicting information related to oxidative stress status in patients with chronic idiopathic urticaria has been reported in several studies. However, the association between acute urticaria (AU) and oxidative stress has not been investigated exhaustively. To evaluate the role of
Houssine Sehaqui et al.
Carbohydrate polymers, 135, 334-340 (2015-10-11)
Cationic cellulose nanofibers (CNF) having 3 different contents of positively charged quaternary ammonium groups have been prepared from waste pulp residues according to a water-based modification method involving first the etherification of the pulp with glycidyltrimethylammonium chloride followed by mechanical
Bergthóra S Snorradóttir et al.
Journal of pharmaceutical sciences, 103(8), 2366-2375 (2014-07-06)
A model is presented for transdermal drug delivery from single-layered silicone matrix systems. The work is based on our previous results that, in particular, extend the well-known Higuchi model. Recently, we have introduced a numerical transient model describing matrix systems
Vishal D Shah et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 54(6), 799-802 (2015-12-04)
During the acclimation phase of a preclinical safety study involving Syrian golden hamsters, some of the cages of treatment-naïve animals were noted to contain blue-tinged bedding; the urine of these hamsters was not discolored. We sought to understand the underlying
Nađa Kostić et al.
Journal of pharmaceutical and biomedical analysis, 109, 79-84 (2015-03-15)
In this paper, novel LC-MS/MS methods for the determination of antiepileptic drug pregabalin in dried matrix spots (DMS) are presented. This attractive technique of sample collection in micro amount was utilized in the form of dried blood spots (DBS) and
Radka Křikavová et al.
PloS one, 9(9), e107373-e107373 (2014-09-17)
A series of gold(I) complexes involving triphenylphosphine (PPh3) and one N-donor ligand derived from deprotonated mono- or disubstituted hypoxanthine (HLn) of the general composition [Au(Ln)(PPh3)] (1-9) is reported. The complexes were thoroughly characterized, including multinuclear high resolution NMR spectroscopy as
Quoc-Chon Le et al.
Colloids and surfaces. B, Biointerfaces, 123, 150-157 (2014-09-23)
A systematic study was carried out on monolayer films and lipid vesicles to elucidate the interactions between membrane lipids and commercial particles of titanium dioxide TiO2 (TiO2-P25). Pressure-area isotherms of lipids at various pH values were recorded on a Langmuir
Cyndia A González-Arias et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 74, 249-254 (2014-12-03)
The contamination of food commodities by fungal toxins has attracted great interest because many of these mycotoxins are responsible for different diseases, including cancer and other chronic illnesses. Ochratoxin A (OTA) is a mycotoxin naturally present in food, and long-term
Luis O'mar Serrano Figueroa et al.
Extremophiles : life under extreme conditions, 19(6), 1183-1192 (2015-10-07)
Soap Lake, located in Washington State, is a naturally occurring saline and alkaline lake. Several organisms inhabiting this lake have been identified as producers of siderophores that are unique in structure. Bacterial isolates, enriched from Soap Lake sediment and water
Claire Chatelle et al.
Antioxidants & redox signaling, 23(12), 945-957 (2015-07-21)
Posttranslational formation of disulfide bonds is essential for the folding of many secreted proteins. Formation of disulfide bonds in a protein with more than two cysteines is inherently fraught with error and can result in incorrect disulfide bond pairing and
B Frohm et al.
Soft matter, 11(2), 414-421 (2014-11-20)
The peptide GSFSIQYTYHV derived from human semenogelin I forms a transparent hydrogel through spontaneous self-assembly in water at neutral pH. Linear rheology measurements demonstrate that the gel shows a dominating elastic response over a large frequency interval. CD, fluorescence and
Chiara E Ghezzi et al.
Biomaterials, 35(24), 6236-6247 (2014-05-14)
Airway tracts serve as a conduit of transport in the respiratory system. Architecturally, these are composed of cartilage rings that offer flexibility and prevent collapse during normal breathing. To this end, the successful regeneration of an airway tract requires the
Alice J S Fox et al.
The American journal of sports medicine, 42(12), 2851-2859 (2014-08-22)
Recent studies suggest that fluoroquinolone antibiotics predispose tendons to tendinopathy and/or rupture. However, no investigations on the reparative capacity of tendons exposed to fluoroquinolones have been conducted. Fluoroquinolone-treated animals will have inferior biochemical, histological, and biomechanical properties at the healing
Cecilia Fortugno et al.
Journal of pharmaceutical and biomedical analysis, 95, 151-157 (2014-04-01)
Bicalutamide (Casodex®) is a non-steroidal anti-androgen drug used in the treatment of prostate cancer, which represents the second most common malignancy diagnosed in men worldwide. In this work, we analyze the ability of some novel bicalutamide analogs to bind the
Hamid Reza Moazami et al.
Analytica chimica acta, 841, 24-32 (2014-08-12)
In order to understand the limitations of electromebrane extraction procedure better, a simple equivalent circuit has been proposed for a supported liquid membrane consisting of a resistor and a low leakage capacitor in series. To verify the equivalent circuit, it
Anne Bellon et al.
Transfusion, 54(4), 1028-1036 (2013-09-17)
The high resistance of prions to inactivating treatments requires the proper management of decontaminating procedures of equipment in contact with materials of human or animal origin destined for medical purposes. Sodium hydroxide (NaOH) is widely used today for this purpose
Kathirvel Gopalakrishnan et al.
Hypertension (Dallas, Tex. : 1979), 65(1), 200-210 (2014-11-12)
Long noncoding RNAs (lncRNAs) are an emerging class of genomic regulatory molecules reported in various species. In the rat, which is one of the major mammalian model organisms, discovery of lncRNAs on a genome-wide scale is lagging. Renal lncRNA sequencing
Chien-Liang Liu et al.
Small (Weinheim an der Bergstrasse, Germany), 10(19), 3962-3969 (2014-07-22)
The room-temperature, aqueous-phase synthesis of iron-oxide nanoparticles (IO NPs) with glutathione (GSH) is reported. The simple, one-step reduction involves GSH as a capping agent and tetrakis(hydroxymethyl)phosphonium chloride (THPC) as the reducing agent; GSH is an anti-oxidant that is abundant in
Daniel J O'Sullivan et al.
BMC microbiology, 15, 266-266 (2015-11-19)
The aim of this study was to employ high-throughput DNA sequencing to assess the incidence of bacteria with biogenic amine (BA; histamine and tyramine) producing potential from among 10 different cheeses varieties. To facilitate this, a diagnostic approach using degenerate
Shu-Ling Lin et al.
Talanta, 147, 199-206 (2015-11-26)
In this study, recently developed 1,6-hexanediol ethoxylate diacrylate (HEDA)-based polymeric monoliths were utilized as sorbents for efficient extraction of phenylurea herbicides (PUHs) from water samples. The HEDA-based monolithic sorbents were prepared in a fused silica capillary (0.7mm i.d., 4.5-cm long)
Lucy G Chastain et al.
Behavioural brain research, 280, 160-171 (2014-12-03)
Schizophrenia is thought to be caused, at least in part, by dysfunction in striatal dopamine neurotransmission. Both clinical studies and animal research have implicated the dopamine neuromodulator neurotensin (NT) in the pathophysiology of schizophrenia. Utilizing male mice lacking the NT
Davy Baudelet et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 35-43 (2015-02-24)
The P2X receptors are seven-transmembrane domain G protein-coupled receptors and the 7 subtypes of P2X receptors identified in humans, and named P2X1 to P2X7, are channel receptors whose endogenous ligand is ATP. New antagonists of the P2X7 receptor were developed
Rui Cheng et al.
Investigative ophthalmology & visual science, 54(5), 3400-3409 (2013-04-25)
Without therapeutic intervention, corneal neovascularization rapidly compromises visual acuity, and is a leading cause of blindness. Artesunate was reported to inhibit angiogenesis in tumors, although, the effects of artesunate on nontumor angiogenesis have not been investigated. This study was designed
Barbara Simonato et al.
Food chemistry, 174, 219-225 (2014-12-23)
The aim of this study was to assess the digestibility of the protein and starch in pasta made with different cereals, i.e. Triticum durum, Triticum polonicum and Triticum dicoccum, and to measure the glycemic index (GI) of the different types
Venkata V V R Marada et al.
Pharmacological research, 91, 78-87 (2014-12-08)
The ability of an antineoplastic drug to exert its cytostatic effect depends largely on the balance between its uptake into and extrusion from the cancer cells. ATP driven efflux transporter proteins drive the export of antineoplastic drugs and play a
N G R Dayan Elshan et al.
Organic & biomolecular chemistry, 13(6), 1778-1791 (2014-12-17)
Melanocortin receptors can be used as biomarkers to detect and possibly treat melanoma. To these ends, molecules bearing one, two, or three copies of the weakly binding ligand MSH(4) were attached to scaffolds based on phloroglucinol, tripropargylamine, and 1,4,7-triazacyclononane by
Anna Sankiewicz et al.
Analytical biochemistry, 469, 4-11 (2014-10-15)
We have developed a new method for highly selective determination of the ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) concentration using a surface plasmon resonance imaging (SPRI) technique and two different biosensors. UCH-L1 was captured from a solution by immobilized specific rabbit
Leila Bagheri et al.
Journal of microencapsulation, 31(7), 636-643 (2014-04-29)
Whey proteins were inter-connected either by the enzyme transglutaminase or citric acid and then desolvated with ethanol to generate particles. Both samples comprised of sub-micron (>300 nm) and nano-scaled (~100 nm) particles based on the hydrodynamic size measurements. Enzyme-induced cross-linking
Rokhsana Yasmin et al.
Journal of pharmaceutical sciences, 103(9), 2950-2959 (2014-03-04)
Lyophilization was investigated to produce a powdery silica-lipid hybrid (SLH) carrier for oral delivery of poorly water-soluble drugs. The silica to lipid ratio, incorporation of cryoprotectant, and lipid loading level were investigated as performance indicators for lyophilized SLH carriers. Celecoxib
M Argun et al.
Eye (London, England), 28(6), 752-760 (2014-03-08)
Under conditions of oxidative stress, cell apoptosis is triggered through the mitochondrial intrinsic pathway. Increased levels of reactive oxygen species (ROS) are linked to excess cell loss and mediate the initiation of apoptosis in a diverse range of cell types.
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