Showing 1-13 of 13 resultados for "


Kenneth A Kudsk et al.
The Journal of trauma, 64(2), 316-323 (2008-02-28)
Secretory immunoglobulin A (SIgA) is the specific immune antibacterial defense. Since pneumonia frequently complicates the course of trauma patients, we studied early airway immune responses after injury. Twelve severely injured, intubated (expected for >/=5 d) patients had tracheal and bilateral...
A J Macpherson
Current topics in microbiology and immunology, 308, 117-136 (2006-08-23)
The lower intestine of mammals is colonised by a dense flora composed mainly of non-pathogenic commensal bacteria. These intestinal bacteria have a wide-ranging impact on host immunity and physiology. One adaptation following intestinal colonisation is increased production and secretion of...
Emma Slack et al.
Frontiers in immunology, 3, 100-100 (2012-05-09)
Intestinal bacteria outnumber our own human cells in conditions of both health and disease. It has long been recognized that secretory antibody, particularly IgA, is produced in response to these microbes and hypothesized that this must play an important role...
Alpha Fardah Athiyyah et al.
Iranian journal of microbiology, 11(4), 300-304 (2019-11-14)
Probiotics and prebiotics are known to regulate immune responses. A synbiotic is a product that combines probiotics and prebiotics in a single dosage form. In this study, we attempt to present the effects of a multispecies synbiotic on intestinal mucosa...
Shimpei Kawamoto et al.
Science (New York, N.Y.), 336(6080), 485-489 (2012-04-28)
Immunoglobulin A (IgA) is essential to maintain the symbiotic balance between gut bacterial communities and the host immune system. Here we provide evidence that the inhibitory co-receptor programmed cell death-1 (PD-1) regulates the gut microbiota through appropriate selection of IgA...
Salivary antibody response to vaccination with meningococcal A/C polysaccharide vaccine in previously vaccinated and unvaccinated Gambian children
Nurkka A, et al.
Vaccine, 19(4-5), 547-556 (2000)
A Aase et al.
Mucosal immunology, 9(4), 884-893 (2015-10-29)
Whole-saliva IgA appears like an attractive noninvasive readout for intestinal immune induction after enteric infection or vaccination, but has failed to show consistent correlation with established invasive markers and IgA in feces or intestinal lavage. For reference, we measured antibodies...
B Simell et al.
The Journal of infectious diseases, 183(6), 887-896 (2001-03-10)
Local antibodies probably contribute to defense against Streptococcus pneumoniae. This study examined whether pneumococcal carriage and acute otitis media (AOM) induce mucosal antibodies to potential vaccine candidates pneumococcal surface adhesin A (PsaA), pneumolysin (Ply), and pneumococcal surface protein A (PspA)....
Influence of reactive oxygen species on secretory component in the intestinal epithelium during hyperoxia
Zhao M, et al.
Experimental and Therapeutic Medicine, 14(5), 4033-4040 (2017)
Solange de Paula Ramos et al.
European journal of orthodontics, 33(5), 584-591 (2011-02-09)
The aim of this study was to analyse serum IgG levels and salivary secretory IgA (sIgA) levels in human dentine extract (HDE) before (T0) and 6 months after (T6) orthodontic treatment and to correlate anti-HDE autoantibodies to root resorption. Fifty...
Muna Sapkota et al.
Alcoholism, clinical and experimental research, 41(12), 2093-2099 (2017-09-25)
Malondialdehyde (MDA) and acetaldehyde (AA) exist following ethanol metabolism and tobacco pyrolysis. As such, lungs of individuals with alcohol use disorders (AUDs) are a target for the effects of combined alcohol and cigarette smoke metabolites. MDA and AA form a...
Ann-Kristin Molvaersmyr et al.
Nucleic acids research, 38(15), 4970-4984 (2010-04-14)
Synergy between transcription factors operating together on complex promoters is a key aspect of gene activation. The ability of specific factors to synergize is restricted by sumoylation (synergy control, SC). Focusing on the haematopoietic transcription factor c-Myb, we found evidence...
Min Zhao et al.
Experimental and therapeutic medicine, 14(5), 4033-4040 (2017-10-28)
Redox imbalance is established in various human diseases. Treatment of intestinal epithelial cells with hyperoxia for a prolonged period of time may cause serious effects on redox balance. Secretory component (SC) protein is secreted by intestinal epithelial cells, and has...