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M7894

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Palabra clave:'M7894'
Mostrando 1-30 of 38 resultados para "M7894" en el plazo de Papeles
J Zhu et al.
American journal of respiratory and critical care medicine, 164(12), 2220-2228 (2001-12-26)
We wished to determine if the inflammatory cells surrounding the airway mucus-secreting glands in chronic bronchitis (CB) were associated with interleukin (IL)-4 and IL-5 mRNA expression and whether the CD8 T cell population expressed these cytokines. Digoxigenin-labeled IL-4 and IL-5
Thomas Lion et al.
Methods in molecular medicine, 125, 275-295 (2006-03-01)
Molecular monitoring of hematopoietic chimerism has become a routine diagnostic approach in patients after allogeneic stem cell transplantation. Chimerism testing permits the documentation and surveillance of engraftment and facilitates early detection of impending graft rejection. In patients transplanted for treatment
Hideki Hosono et al.
International journal of molecular medicine, 46(4), 1443-1452 (2020-09-19)
The epidermal growth factor receptor (EGFR), a transmembrane receptor and member of the human epidermal growth factor receptor (HER) family of receptor tyrosine kinases, is a critical mediator of cell growth and differentiation. EGFR forms homo‑ or heterodimers with other
Tue W Kragstrup et al.
Arthritis research & therapy, 16(1), R42-R42 (2014-02-05)
Spondyloarthritis (SpA) comprises a group of diseases often associated with HLA-B27 and characterized by inflammation of the entheses and joints of the axial skeleton. The inflammatory process in SpA is presumably driven by innate immune cells but is still poorly
Wiltrud Lederle et al.
International journal of cancer, 128(12), 2803-2814 (2010-08-21)
Cytokines play a crucial role in tumor initiation and progression. Here, we demonstrate that interleukin (IL)-6 is a key factor by driving tumor progression from benign to malignant, invasive tumors in the HaCaT-model of human skin carcinoma. IL-6 activates STAT3
Jonathan J Miner et al.
Cell reports, 33(5), 108339-108339 (2020-11-05)
Here, we report our studies of immune-mediated regulation of Zika virus (ZIKV), herpes simplex virus 1 (HSV-1), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the human cornea. We find that ZIKV can be transmitted via corneal transplantation
M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis
Schlapbach LJ, et al.
Pediatric Research, 71(4-1), 368-368 (2012)
J Zhu et al.
American journal of respiratory and critical care medicine, 164(1), 109-116 (2001-07-04)
Eosinophilia has been reported during exacerbations of bronchitis, but the mechanisms of tissue recruitment of eosinophils are unclear. We quantified eosinophils and the concurrent expression of cytokines and chemokines probably responsible for the tissue eosinophilia in bronchial biopsies obtained from
Ruben J Boado et al.
Biotechnology and bioengineering, 102(4), 1251-1258 (2008-10-23)
Protein therapeutics may be delivered across the blood-brain barrier (BBB) by genetic fusion to a BBB molecular Trojan horse. The latter is an endogenous peptide or a peptidomimetic monoclonal antibody (MAb) against a BBB receptor, such as the insulin receptor
Eva Obermueller et al.
Cancer research, 64(21), 7801-7812 (2004-11-03)
Tumor growth and progression are critically controlled by alterations in the microenvironment often caused by an aberrant expression of growth factors and receptors. We demonstrated previously that tumor progression in patients and in the experimental HaCaT tumor model for skin
IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines
Lederle W, et al.
International Journal of Cancer. Journal International Du Cancer, 128(12), 2803-2814 (2011)
Irene Kyrmizi et al.
Journal of leukocyte biology, 94(4), 751-757 (2013-07-31)
The MAPK3 Tpl2 controls innate and adaptive immunity by regulating TLR, TNF-α, and GPCR signaling in a variety of cell types. Its ablation gives rise to an anti-inflammatory phenotype characterized by resistance to LPS-induced endotoxin shock, DSS-induced colitis, and TNF-α-induced
Thomas Lion
Methods in molecular medicine, 134, 197-216 (2007-08-02)
Molecular surveillance of hematopoietic chimerism has become part of the routine diagnostic program in patients after allogeneic stem cell transplantation. Chimerism testing permits early prediction and documentation of successful engraftment, and facilitates early detection of impending graft rejection. In patients
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG
Anna Haeger et al.
The Journal of experimental medicine, 217(1) (2019-10-30)
Cancer fatalities result from metastatic dissemination and therapy resistance, both processes that depend on signals from the tumor microenvironment. To identify how invasion and resistance programs cooperate, we used intravital microscopy of orthotopic sarcoma and melanoma xenografts. We demonstrate that
Stacy Hu et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 32(4), 203-210 (2016-01-16)
The purpose of this study was to determine whether nonspecific and ICAM-1-specific IgG1 antibodies can accumulate in the rat retina following topical application, and to develop a model system to show that antibodies that reach the posterior segment retain their
Weili Liu et al.
Protein & cell, 9(9), 785-798 (2017-05-26)
Leukocyte differentiation antigens (LDAs) play important roles in the immune system, by serving as surface markers and participating in multiple biological activities, such as recognizing pathogens, mediating membrane signals, interacting with other cells or systems, and regulating cell differentiation and
Jie Zhu et al.
American journal of respiratory cell and molecular biology, 27(6), 666-677 (2002-11-22)
15-lipoxygenase (15-LO) has been implicated in the inflammation of chronic bronchitis (CB), but it is unclear which of its isoforms, 15-LOa or 15-LOb, is primarily involved. To detect 15-LO gene (mRNA) and protein expression, we have applied in situ hybridization
DNA counterstaining for methylation and hydroxymethylation immunostaining in bovine zygotes
Heras S, et al.
Analytical biochemistry, 454, 14-16 (2014)
Tomokazu Ohishi et al.
International journal of molecular sciences, 21(17) (2020-08-26)
The now clinically-used anti-epidermal growth factor receptor (EGFR) monoclonal antibodies have demonstrated significant efficacy only in patients with metastatic colorectal cancer (mCRC), with wild-type Kirsten rat sarcoma viral oncogene homolog (KRAS). However, no effective treatments for patients with mCRC with
Maria Teresa Neves-Petersen et al.
Protein science : a publication of the Protein Society, 15(2), 343-351 (2006-01-26)
Photonic induced immobilization is a novel technology that results in spatially oriented and spatially localized covalent coupling of biomolecules onto thiol-reactive surfaces. Immobilization using this technology has been achieved for a wide selection of proteins, such as hydrolytic enzymes (lipases/esterases
Tue Wenzel Kragstrup et al.
PloS one, 11(2), e0148486-e0148486 (2016-02-06)
In rheumatoid arthritis (RA) immune activation and presence of autoantibodies may precede clinical onset of disease, and joint destruction can progress despite remission. However, the underlying temporal changes of such immune system abnormalities in the inflammatory response during treat-to-target strategies
Differentiation of embryonic stem cells conditionally expressing neurogenin 3
Treff NR, et al.
Stem Cells, 24(11), 2529-2537 (2006)
Specific IgG for cat allergens in patients with allergic conjunctivitis.
Miyama A, et al.
International Ophthalmology, 35(4), 575-586 (2015)
Søren E Degn et al.
Journal of immunological methods, 361(1-2), 37-50 (2010-08-03)
The lectin pathway of complement is part of the innate immune system. The complement-activating pattern-recognition molecules (for which we suggest the abbreviation CAPREMs) mannan-binding lectin (MBL) and the three ficolins (H-, L- and M-ficolin) circulate in complexes with MBL-associated serine
Claudia M Gutschalk et al.
Cancer medicine, 2(2), 117-129 (2013-05-02)
Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes tumor progression in different tumor models in an autocrine and paracrine manner. However, at the same time GM-CSF is used in cancer therapies to ameliorate neutropenia. We have previously shown in GM-CSF and G-CSF expressing
GM-CSF enhances tumor invasion by elevated MMP-2,-9, and-26 expression
Gutschalk CM, et al.
Cancer Medicine, 2(2), 117-129 (2013)
Mattias Fransson et al.
Respiratory research, 8, 17-17 (2007-03-03)
Allergic rhinitis is an inflammatory disease of the upper airway mucosa that also affects leukocytes in bone marrow and peripheral blood. Toll-like receptor 9 (TLR9) is a receptor for unmethylated CpG dinucleotides found in bacterial and viral DNA. The present
The amino acid sequence of a human ? light chain
Milstein CP, et al.
The Biochemical Journal, 123(5), 945-958 (1971)
A Sharland et al.
Transplantation, 65(10), 1370-1377 (1998-06-13)
Liver transplants in the rat strain combination PVG-to-Dark Agouti are spontaneously tolerated, whereas kidney transplants in the same strain combination are rejected in 7-9 days. To identify organ-specific differences that might yield further information about the mechanism of tolerance induction
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