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Yan Li et al.
Journal of cellular physiology, 234(11), 20298-20309 (2019-04-12)
The metabolism of immune cells reprograms inflammatory responses to protect against infection by pathogenic microorganisms, but the immune effects of glycolysis and the oxidative phosphorylation (OXPHOS) metabolic pathway remain unclear. Herein, the effects of glycolysis or OXPHOS on the neutrophils...
Wenfeng Xu et al.
Evidence-based complementary and alternative medicine : eCAM, 2019, 8496817-8496817 (2020-01-14)
Niuhuang Jiedu tablet (NJT), a realgar (As2S2) containing Traditional Chinese Medicine (TCM), is a well-known formula. The safety of NJT is of growing concern since arsenic (As) is considered as one of the most toxic elements. NJT was demonstrated to...
Development of a new protocol for the isolation and quantification of Arcobacter species from poultry products
Houf K, et al.
International Journal of Food Microbiology, 71(2-3), 189-196 (2001)
Chie Monma et al.
Journal of clinical microbiology, 53(3), 859-867 (2015-01-09)
The epidemiological and bacteriological investigations on four foodborne outbreaks caused by a new type of enterotoxin-producing Clostridium perfringens are described. C. perfringens isolated from patients of these outbreaks did not produce any known enterotoxin and did not carry the C....
Tanira V Verissimo et al.
Materials science & engineering. C, Materials for biological applications, 65, 199-204 (2016-05-10)
The surface of gold nanoparticles (AuNP) was modified, improving their interaction with neutral red (NR), by using sodium thioglycolate (TGA) as a covering agent. The resulting NR-AuNPTGA system was evaluated as a potential drug delivery system for photodynamic therapy (PDT)....
Elham Atefi Tabar et al.
Folia microbiologica, 64(2), 189-195 (2018-08-29)
Turkeys and broilers have been identified as important reservoirs for Campylobacter jejuni which is of public health significance. The evaluation of the genotypes among C. jejuni strains within different reservoirs is critical for our understanding of the epidemiology of this...
Jihong Li et al.
PloS one, 5(6), e10932-e10932 (2010-06-10)
Clostridium perfringens enterotoxin (encoded by the cpe gene) contributes to several important human, and possibly veterinary, enteric diseases. The current study investigated whether cpe locus organization in type C or D isolates resembles one of the three (one chromosomal and...
Kouhei Oonuma et al.
Developmental biology, 420(1), 178-185 (2016-10-30)
The Ciona intestinalis larva has two distinct photoreceptor organs, a conventional pigmented ocellus and a nonpigmented ocellus, that are asymmetrically situated in the brain. The ciliary photoreceptor cells of these ocelli resemble visual cells of the vertebrate retina. Precise elucidation...
Ruoshuang Zhang et al.
PloS one, 11(1), e0146808-e0146808 (2016-01-14)
Choroidal neovascularization (CNV) is an important pathologic component of neovascular age-related macular degeneration (AMD), and CNV lesions later develop into fibrous scars, which contribute to the loss of central vision. Nowadays, the precise molecular and cellular mechanisms underlying CNV and...
Tanira M Bastos et al.
Antimicrobial agents and chemotherapy, 58(10), 6044-6055 (2014-08-06)
cis-[RuCl(NO2)(dppb)(5,5'-mebipy)] (complex 1), cis-[Ru(NO2)2(dppb)(5,5'-mebipy)] (complex 2), ct-[RuCl(NO)(dppb)(5,5'-mebipy)](PF6)2 (complex 3), and cc-[RuCl(NO)(dppb)(5,5'-mebipy)](PF6)2 (complex 4), where 5,5'-mebipy is 5,5'-dimethyl-2,2'-bipyridine and dppb is 1,4-bis(diphenylphosphino)butane, were synthesized and characterized. The structure of complex 2 was determined by X-ray crystallography. These complexes exhibited a higher...
Cecilia Lindström et al.
AMB Express, 2(1), 66-66 (2012-12-14)
Intake of dietary fibres may reduce the prevalence of physiological risk factors of the metabolic syndrome, such as high plasma lipid levels and low-grade inflammatory state. Dietary fibres are usually of plant origin however microbial exopolysaccharides (EPSs) have analogue structures...
María Tomé et al.
Stem cells (Dayton, Ohio), 32(8), 2229-2244 (2014-03-22)
MicroRNAs, small noncoding RNAs, regulate gene expression primarily at the posttranscriptional level. We previously found that miR-335 is critically involved in the regulation and differentiation capacity of human mesenchymal stem cells (hMSCs) in vitro. In this study, we investigated the...
Jihong Li et al.
mBio, 4(5), e00770-e00713 (2013-10-10)
CodY is known to regulate various virulence properties in several Gram-positive bacteria but has not yet been studied in the important histotoxic and intestinal pathogen Clostridium perfringens. The present study prepared an isogenic codY-null mutant in C. perfringens type D...
Benjamin Bondue et al.
PloS one, 7(6), e40043-e40043 (2012-07-07)
Macrophages constitute a major component of innate immunity and play an essential role in defense mechanisms against external aggressions and in inflammatory responses. Chemerin, a chemoattractant protein, is generated in inflammatory conditions, and recruits cells expressing the G protein-coupled receptor...
Matteo Grattieri et al.
ChemSusChem, 10(9), 2053-2058 (2017-03-01)
Microbial fuel cells are an emerging technology for wastewater treatment, but to be commercially viable and sustainable, the electrode materials must be inexpensive, recyclable, and reliable. In this study, recyclable polymeric supports were explored for the development of anode electrodes...
Michelle D Regulacio et al.
Nanoscale, 5(6), 2322-2327 (2013-02-09)
Highly emissive and air-stable AgInS2-ZnS quantum dots (ZAIS QDs) with quantum yields of up to 20% have been successfully synthesized directly in aqueous media in the presence of polyacrylic acid (PAA) and mercaptoacetic acid (MAA) as stabilizing and reactivity-controlling agents....
Charlien Clauwers et al.
Applied and environmental microbiology, 82(10), 3100-3108 (2016-03-20)
Group II nonproteolytic Clostridium botulinum (gIICb) strains are an important concern for the safety of minimally processed ready-to-eat foods, because they can grow and produce botulinum neurotoxin during refrigerated storage. The principles of control of gIICb by conventional food processing...
Menglin Ma et al.
Journal of bacteriology, 197(10), 1807-1818 (2015-03-18)
The accessory growth regulator (Agr)-like quorum sensing (QS) system of Clostridium perfringens controls the production of many toxins, including beta toxin (CPB). We previously showed (J. E. Vidal, M. Ma, J. Saputo, J. Garcia, F. A. Uzal, and B. A....
Elham Mohagheghpour et al.
IEEE transactions on nanobioscience, 11(4), 317-323 (2012-12-06)
In this research, we mainly focused on the micro-emulsion synthesis of biotinylated ZnS (zinc sulfide) nanocrystals for avidin recognition. Various samples of Zn(1-x)Mn(x) S, with x = 0.0001, 0.007, 0.02, 0.03, 0.055, 0.09 and 0.13, prepared by quaternary W/O (water-in-oil)...
Clarissa X R Valim et al.
PloS one, 7(9), e44792-e44792 (2012-10-02)
Paracoccidioides brasiliensis is the etiologic agent of paracoccidioidomycosis (PCM), one of the most prevalent mycosis in Latin America. P. brasiliensis cell wall components interact with host cells and influence the pathogenesis of PCM. Cell wall components, such as glycosylphosphatidylinositol (GPI)-proteins...
Jihong Li et al.
PLoS pathogens, 7(12), e1002429-e1002429 (2011-12-17)
Clostridium perfringens type B or D isolates, which cause enterotoxemias or enteritis in livestock, produce epsilon toxin (ETX). ETX is exceptionally potent, earning it a listing as a CDC class B select toxin. Most C. perfringens strains also express up...
Samantha R Soncini et al.
BMC genomics, 21(1), 45-45 (2020-01-16)
Clostridium perfringens is a Gram-positive anaerobic pathogen that causes multiple diseases in humans and animals. C. perfringens lack flagella but have type IV pili (TFP) and can glide on agar surfaces. When C. perfringens bacteria are placed on surfaces, they...
Jeremy R Duvall et al.
ACS infectious diseases, 3(5), 349-359 (2017-02-22)
In 2013, the Centers for Disease Control highlighted Clostridium difficile as an urgent threat for antibiotic-resistant infections, in part due to the emergence of highly virulent fluoroquinolone-resistant strains. Limited therapeutic options currently exist, many of which result in disease relapse....
Diana Granados-Falla et al.
Parasitology, 143(3), 289-299 (2015-12-24)
The rational search of novel bioactive molecules against pathogens with immunomodulatory activity is presently one of the most significant approaches to discover and design new therapeutic agents for effective control of infectious diseases, such as the infection caused by Leishmania...
Lars Bellner et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(1), 105-115 (2014-10-25)
Heme oxygenase (HO)-2 deficiency impairs wound healing and exacerbates inflammation following injury. We examine the impact of HO-2 deficiency on macrophage function and the contribution of macrophage HO-2 to inflammatory and repair responses to injury. Corneal epithelial debridement was performed...
Kazuaki Miyamoto et al.
Journal of bacteriology, 190(21), 7178-7188 (2008-09-09)
Clostridium perfringens type B and D isolates produce epsilon-toxin, the third most potent clostridial toxin. The epsilon-toxin gene (etx) is plasmid borne in type D isolates, but etx genetics have been poorly studied in type B isolates. This study reports...
Zhenzhen Chen et al.
Biosensors & bioelectronics, 44, 204-209 (2013-02-23)
A novel turn-on and turn-off sensor based on the fluorescence change of quantum dots (QDs) has been developed to detect the activity of butyrylcholinesterase (BChE). In the turn-on sensing system, we realized the detection of BChE with just one enzyme....
Anjana Chakravorty et al.
PloS one, 6(7), e22762-e22762 (2011-08-11)
Clostridium perfringens is the causative agent of clostridial myonecrosis or gas gangrene and produces many different extracellular toxins and enzymes, including the cysteine protease α-clostripain. Mutation of the α-clostripain structural gene, ccp, alters the turnover of secreted extracellular proteins in...
K A Weedmark et al.
Applied and environmental microbiology, 81(17), 5938-5948 (2015-06-28)
Clostridium botulinum group II isolates (n = 163) from different geographic regions, outbreaks, and neurotoxin types and subtypes were characterized in silico using whole-genome sequence data. Two clusters representing a variety of botulinum neurotoxin (BoNT) types and subtypes were identified...
Pengcheng Yan et al.
Marine drugs, 8(11), 2837-2848 (2010-12-09)
Chemical examination of a Chinese soft coral Lobophytum pauciflorum resulted in the isolation of five new biscembranoids named lobophytones O-S (1-5) and a new "monomeric" cembrane lobophytone T (6). The structures of the new compounds were elucidated by interpretation of...
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