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Analytical Chemistry Learning Hub

Introduction

Analytical chemistry serves as the cornerstone for accurate measurement and quality assurance in various sectors, such as pharmaceuticals and life sciences, along with environmental and food testing. This learning hub provides crucial insights, strategies, and resources to enhance precise measurement, method development, and data dependability. Discover resources related to chromatographic separation, spectroscopy, sample preparation, and method validation to remain at the cutting edge of analytical innovation.

Section Overview

Introduction

Featured Articles

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Analysis of PFAS in Water according to EPA 1633

LC-MS/MS determination of per- and polyfluoroalkyl substances (PFAS) in water samples using Supelclean™ ENVI-WAX™ SPE cartridges as per EPA Method 1633.

Sample Cleanliness Using BioSPME

Learn about Supel™ BioSPME C18 96-pin tool to prepare a clean sample with minimal matrix effects for an LC-MS/MS analysis from human plasma and its comparison with acetonitrile-based precipitation.

GC-MS Analysis of Lithium Ion Battery Electrolyte Solvents

Analysis of carbonate solvents in lithium-ion batteries like ethylene carbonate, dimethyl carbonate, diethyl carbonate, and more using SPB^®-624 column.

N-Nitrosamines Determination in Valsartan

GC-MS method detects nitrosamines in Valsartan tablets, meeting US FDA guidelines for pharmaceutical quality control.

The Carbon Enigma: Material Fundamentals and Retention Properties for Porous Graphitic Carbon (PGC) Stationary Phases

A shortened review of fundamentals of Porous Graphitic Carbon (PGC) materials. What they are and how do they work as a stationary phase material in HPLC?

Cannabinoid CRMs: Testing Accuracy & Traceability

ISO-certified cannabinoid CRMs, THC and THCA, available as single components or mixes, for accurate potency testing.

Analytical Chemistry Techniques and Technologies

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Small Molecule HPLC

Explore HPLC techniques, columns, and sample prep strategies for precise analysis and separation of small molecules across complex sample matrices.

Gas Chromatography (GC)

Explore essential tools, techniques, and products for gas chromatography to support accurate, efficient, and reliable analytical chemistry workflows.

Solid Phase Extraction (SPE)

Explore solid phase extraction (SPE) techniques, products, and protocols to achieve cleaner samples and improve accuracy in analytical workflows.

Mass Spectrometry

Learn about mass spectrometry and explore products and resources for accurate identification, quantification, and analysis across applications.

Titration & Karl Fischer Analysis

Discover techniques, workflows, and resources to master precise volumetric and Karl Fischer methods for accurate content determination and analysis.

Thin Layer Chromatography

Learn TLC principles, workflows, and applications for separating and analyzing diverse compounds in food, pharma, cosmetics, and environmental samples.

Resources Library

Recommended Readings

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Article: HPLC Troubleshooting Guide

Fix common HPLC issues affecting peak shape, retention time, noise, and resolution with practical guidance and example chromatograms.

A person performing Thin Layer Chromatography (TLC), a technique used in chemistry to separate and analyze compounds in a mixture.

Article: Tips & Tricks for Thin-Layer Chromatography

Troubleshooting guide for thin-layer chromatography to enhance sample application, development, and visualization, and address common problems.

a pyramid diagram representing different levels of certification and traceability for reference materials, typically used in laboratories to ensure quality control, calibration, and validation of methods.

Article: Choosing Correct Reference Material Quality Grade

Reference materials, standards and certified reference materials are critical for analytical testing. We can help you to choose the ideal reference material for your application, whether you are using

High-Performance Liquid Chromatography (HPLC) columns, which are essential components of an HPLC system used in analytical chemistry.

Article: USP HPLC Columns

Explore our full selection of USP HPLC columns, from L1 to L45, made for accurate and reliable separations in a wide range of applications.

A Solid-Phase Microextraction (SPME) fiber assembly, a tool used in sample preparation for analytical techniques such as Gas Chromatography (GC) or GC-MS (Gas Chromatography-Mass Spectrometry).

Article: Nitinol Core SPME Fibers for Improved Fiber Reproducibility

A comparison between Carboxen^®/PDMS coated nitinol core and fused silica core adsorbent SPME fibers for factors.

A schematic diagram of an ion chromatography system setup. Ion chromatography is a technique used to separate and analyze ions in a solution.

Ion Chromatography Instrument Qualification using IQ/OQ/PQ Kit

Explore key tests in ion chromatography qualification using a pre-packaged IQ/OQ/PQ kit with six certified bromide standards for IC performance checks.