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Merck

M1880

Magnesium sulfate heptahydrate

ReagentPlus®, ≥99.0%

Magnesium sulfate heptahydrate

Synonym(s):

Epsom salts

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500 G

€52.10

1 KG

€101.00

5 KG

€352.00

€52.10


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About This Item

Linear Formula:
MgSO4 · 7H2O
CAS Number:
Molecular Weight:
246.47
EC Number:
MDL number:
UNSPSC Code:
12352302
eCl@ss:
38030409
PubChem Substance ID:
NACRES:
NA.21
Assay:
≥99.0%
Form:
powder or crystals

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vapor density

<0.01 (vs air)

Quality Level

vapor pressure

<0.1 mmHg ( 20 °C)

product line

ReagentPlus®

Assay

≥99.0%

form

powder or crystals

pH

5-8 (50 g/L)

SMILES string

O.O.O.O.O.O.O.[Mg++].[O-]S([O-])(=O)=O

InChI

1S/Mg.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2

InChI key

WRUGWIBCXHJTDG-UHFFFAOYSA-L

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This Item
2303919405181374361
form

powder or crystals

form

crystals

form

powder or crystals

form

-

assay

≥99.0%

assay

≥98%, 98.0-102.0% (ACS specification)

assay

≥98% (EDTA titration), ≥99.9% trace metals basis

assay

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-

vapor pressure

<0.1 mmHg ( 20 °C)

vapor pressure

<0.1 mmHg ( 20 °C)

vapor pressure

<0.1 mmHg ( 20 °C)

vapor pressure

<0.1 mmHg ( 20 °C)

pH

5-8 (50 g/L)

pH

5.0-8.2 (25 °C, 5%)

pH

-

pH

-

vapor density

<0.01 (vs air)

vapor density

<0.01 (vs air)

vapor density

<0.01 (vs air)

vapor density

<0.01 (vs air)

General description

Magnesium sulfate heptahydrate is hydrated salt of magnesium sulfate. It is hygroscopic in its anhydrous form. It can be used as a hydrophilic additive and as a catalyst in organic synthesis.

Application

Magnesium sulfate heptahydrate is used:
  • As an effective,catalyst for the condensation of o-phenylenediamine and 1,2-dicarbonyl compounds at room temperature.
  • As a catalyst in the synthesis of tri/tetra-substituted imidazoles from wide range of aromatic aldehydes, benzil, aliphatic and aromatic primary amines and ammonium acetate.
  • In the preparation of amorphous magnesium borates of various composition by interacting with sodium borate decahydrate.

Magnesium sulfate heptahydrate may be used as a catalyst for the condensation of o-phenylenediamines with 1,2-dicarbonyl compounds to form phenazine and quinoxaline derivatives.[1] It may also be used as a catalyst along with indium (III) triflate for the synthesis of tri/tetra-substituted imidazoles.[2]

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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New conditions for the effective synthesis of tri and tetrasubstituted imidazoles catalysed by recyclable indium (III) triflate and magnesium sulfate heptahydrate.
Karami B, et al.
J. Chem. Res. (M), 38(1), 41-45 (2014)
Size-dependent growth of magnesium sulfate heptahydrate.
Rousseau RW and Parks RM.
Industrial & Engineering Chemistry Fundamentals, 20(1), 71-76 (1981)
A facile synthesis of phenazine and quinoxaline (new 1,4-benzo diazine) derivatives using magnesium sulfate heptahydrate as a catalyst.
Karami B and Khodabakhshi S.
J. Serb. Chem. Soc., 76(9), 1191-1198 (2011)
Shoshana Naiman et al.
Cell reports, 29(12), 4127-4143 (2019-12-19)
The pro-longevity enzyme SIRT6 regulates various metabolic pathways. Gene expression analyses in SIRT6 heterozygotic mice identify significant decreases in PPARα signaling, known to regulate multiple metabolic pathways. SIRT6 binds PPARα and its response element within promoter regions and activates gene transcription.
Karen J Gibbins et al.
Obstetrics and gynecology, 121(2 Pt 1), 235-240 (2013-01-25)
Clinical trials support the efficacy and safety of magnesium sulfate for cerebral palsy prevention. We evaluated the implementation of a clinical protocol for the use of magnesium for cerebral palsy prevention in our large women's hospital, focusing on uptake, indications

Protocols

To measure 5′-nucleotidase activity, this procedure uses adenosine 5’-monophosphate and a color reagent to create a standard curve for determining the micromoles of phosphorus liberated.

Measure luciferase activity using a luminometer assay detecting light emission, with applications in ATP detection and genetic function reporting.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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