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238813

Sigma-Aldrich

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

97%

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Synonym(s):
Trolox
Empirical Formula (Hill Notation):
C14H18O4
CAS Number:
53188-07-1
Molecular Weight:
250.29
Beilstein:
1384051
EC Number:
258-422-8
MDL number:
MFCD00006846
PubChem Substance ID:
24854347
NACRES:
NA.22

Quality Level

200

Assay

97%

storage condition

under inert gas

mp

187-189 °C (lit.)

storage temp.

2-8°C

SMILES string

Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O

InChI

1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)

InChI key

GLEVLJDDWXEYCO-UHFFFAOYSA-N

Gene Information

rat ... Akr1b1(24192)

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1 of 4

This Item
253847391913532576
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid 97%

Sigma-Aldrich

238813

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

2,3,4-Trihydroxybenzoic acid 97%

Sigma-Aldrich

253847

2,3,4-Trihydroxybenzoic acid

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 98%

Sigma-Aldrich

391913

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

Chromone-3-carboxylic acid 97%

Sigma-Aldrich

532576

Chromone-3-carboxylic acid

mp

187-189 °C (lit.)

mp

~205 °C (dec.) (lit.)

mp

162 °C (dec.) (lit.)

mp

202-205 °C (lit.)

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

storage condition

under inert gas

storage condition

-

storage condition

-

storage condition

-

Gene Information

rat ... Akr1b1(24192)

Gene Information

-

Gene Information

-

Gene Information

human ... PTPN1(5770)

General description

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.

Application

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) has been used in 6-hydroxy-2,5,7,8-tetramethyl chromane-2-carboxylic acid equivalent antioxidant assay (TEAC) to determine the total antioxidant capacity of different fruit species.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Functional Analogues of the Dioxygen Reduction Site in Cytochrome Oxidase:? Mechanistic Aspects and Possible Effects of CuB
Boulatov R, et al.
Journal of the American Chemical Society, 124(40), 11923-11923 (2002)
Jessica Scalzo et al.
Nutrition (Burbank, Los Angeles County, Calif.), 21(2), 207-213 (2005-02-23)
We wanted to determine the total antioxidant capacity (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid equivalent antioxidant assay; TEAC) of different species and cultivars (strawberry and apple) and to characterize the TEAC among fruits of the same varieties (peach and apricot) but grafted on different
Dalia Mazor et al.
Biochemical and biophysical research communications, 349(3), 1171-1175 (2006-09-15)
The antioxidant properties of Bucillamine (BUC), a di-thiol compound used for treatment of rheumatoid arthritis (RA) and its possible mode of action, were investigated. BUC exhibits potent antioxidant activity similar to those of trolox and ascorbic acid. It reduces the
Flavonoids as antioxidants
Jovanovic S, et al.
Journal of the American Chemical Society, 116, 4846-4846 (1994)
Leonel N Leal et al.
Journal of the science of food and agriculture, 99(9), 4296-4303 (2019-03-01)
Due to the growing public concern regarding the addition of chemical antioxidants to foods, focus has shifted towards natural alternatives. Because of their antioxidant potential, culinary herbs and spices have long been used to extend the shelf-life of foods. However
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