248886

(1R,2R)-(−)-2-Amino-1-phenyl-1,3-propanediol

98%

• Linear Formula: C₆H₅CH(OH)CH(NH₂)CH₂OH
• CAS Number: 46032-98-8
• Molecular Weight: 167.21
• EC Number: 256-250-8
• MDL number: MFCD00069617
• PubChem Substance ID: 24854958
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• optical activity: [α]23/D −37°, c = 1 in 1 M HCl
• mp: 112-118 °C (lit.)
• SMILES string: N[C@H](CO)[C@H](O)c1ccccc1
• InChI: 1S/C9H13NO2/c10-8(6-11)9(12)7-4-2-1-3-5-7/h1-5,8-9,11-12H,6,10H2/t8-,9-/m1/s1
• InChI key: JUCGVCVPNPBJIG-RKDXNWHRSA-N

Description

Application

(1R,2R)-(−)-2-Amino-1-phenyl-1,3-propanediol can be used as a starting material to prepare:

• Diaryl sulfides, used to synthesize sulfimides and N-tosylsulfimides, applicable as chiral ligands.
• (S,S)-Reboxetine, a selective norepinephrine reuptake inhibitor (NRI).
• L-2-Mercaptosuccinic acid, used in the synthesis of polyester with mercapto group.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves