1.08101

Tetrahydrofuran

≥99.9% (GC), suitable for HPLC, LiChrosolv^®

• Synonym(s): THF, Tetramethylene oxide, Oxolane, Butylene oxide, Butylene oxide, Oxolane, Tetramethylene oxide
• Linear Formula: (CH₂)₃CH₂O
• CAS Number: 109-99-9
• Molecular Weight: 72.11
• NACRES: NA.03
• EC Index Number: 203-726-8
• UNSPSC Code: 12191504
• MDL number: MFCD00005356
• Beilstein/REAXYS Number: 102391
• Assay: ≥99.9% (GC)
• Technique(s): HPLC: suitable
• Bp: 65-67 °C (lit.)
• Vapor pressure: 114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

Properties

• Product Name: Tetrahydrofuran, for liquid chromatography LiChrosolv^®
• Quality Level: 100
• vapor density: 2.5 (vs air)
• vapor pressure: 114 mmHg ( 15 °C), 143 mmHg ( 20 °C)
• description: isocratic
• product line: LiChrosolv^®
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 610 °F
• expl. lim.: 1.8-11.8 %
• technique(s): HPLC: suitable
• impurities: ≤0.0002 meq/g Acidity, ≤0.0002 meq/g Alkalinity, ≤0.02% Peroxide, ≤0.02% Water
• evapn. residue: ≤1.0 mg/L
• transmittance: 218 nm, ≥30%, 230 nm, ≥35%, 250 nm, ≥65%, 280 nm, ≥95%
• refractive index: n20/D 1.407 (lit.)
• pH: 7-8 (20 °C, 200 g/L in H₂O)
• bp: 65-67 °C (lit.)
• mp: −108 °C (lit.)
• transition temp: flash point -20 °C
• density: 0.889 g/mL at 25 °C (lit.)
• storage temp.: 2-30°C
• SMILES string: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChI key: WYURNTSHIVDZCO-UHFFFAOYSA-N

Description

General description

LiChrosolv^® solvents have high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

Application

Used as a solvent in chromatography applications.[1]
Also featured in USP monograph methods for regulated pharmaceutical instrumental analysis.

Features and Benefits

• packaged in glass bottles
• offers high resolution, sensitivity and optimized peak baseline separation

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Evaporation residue: ≤ 1.0 mg/l
Water: ≤ 0.02 %
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Peroxide: ≤ 0.02 %
Transmission (at 218 nm): ≥ 30 %
Transmission (at 230 nm): ≥ 35 %
Transmission (at 250 nm): ≥ 65 %
Transmission (at 280 nm): ≥ 95 %
Filtred by 0.2µm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• signalword: Danger
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• flash_point_f: -6.2 °F - closed cup
• flash_point_c: -21.2 °C - closed cup
• pictograms: GHS02,GHS08,GHS05,GHS07
• hcodes: H225,H302,H318,H335,H336,H351
• pcodes: P202 - P210 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3