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1.42002

SAFC

Calcium chloride dihydrate

EMPROVE® ESSENTIAL Ph Eur,BP,JP,USP,FCC,E 509

Synonym(s):
Calcium dichloride
Empirical Formula (Hill Notation):
CaCl2 · 2H2O
CAS Number:
Molecular Weight:
147.01
MDL number:
E Number:
E509
EC Index Number:
233-140-8

Quality Level

Agency/Method

BP
JP
Ph. Eur.
USP

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

potency

2630 mg/kg LD50, skin (Rat)

pH

4.5-8.5 (20 °C, 50 g/L in H2O)

mp

176 °C (dec.) (lit.)

solubility

1280 g/L

Featured Industry

Pharmaceutical
liquid formulation
semi-solid formulation
solid formulation

storage temp.

15-25°C

SMILES string

O.O.Cl[Ca]Cl

InChI

1S/Ca.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2

InChI key

LLSDKQJKOVVTOJ-UHFFFAOYSA-L

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Calcium chloride dihydrate is a mineral salt typically used as buffering agent in pharmaceutical formulations. Beyond, calcium chloride dihydrate is used as a complexing builder, flavor enhancer and stabilizer for food and beverage.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials.

Material Qualification Dossier

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Quality Management Dossier

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Operational Excellence Dossier

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Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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