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3570

Millipore

Glycine

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Synonym(s):
Glycine, Gly, Aminoacetic acid, Aminoethanoic acid, Glycocoll
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
MDL number:

Assay

>99% (by assay)

Quality Level

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

≤100 CFU/g Total microorganism
≤6.0 EU/g Endotoxin

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

water: 250 mg/mL

cation traces

Fe: ≤10 ppm
heavy metals (as Pb): ≤5 ppm

shipped in

ambient

storage temp.

15-25°C

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

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assay

>99% (by assay)

assay

≥99% (HPLC)

assay

-

assay

≥99%

storage temp.

15-25°C

storage temp.

room temp

storage temp.

20-25°C

storage temp.

room temp

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

solubility

water: 250 mg/mL

solubility

H2O: 200 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

H2O: 200 mg/mL, clear, colorless to faintly yellow

General description

A non-essential, optically inactive, non-chiral amino acid. It is the smallest of the 20 natural amino acids. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.
A nonpolar, uncharged amino acid.

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Warning

Toxicity: Standard Handling (A)

Other Notes

Shapiro, S. 1997. Neurosurgery 40, 168.
Mount, H., et al. 1991. Mol. Pharmacol.39, 205.
Thompson, A.M., et al. 1989. Nature338, 422.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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