85429

Sinapic acid

matrix substance for MALDI-MS, ≥99.0% (T)

• Synonym(s): 3,5-Dimethoxy-4-hydroxycinnamic acid, 4-Hydroxy-3,5-dimethoxy-cinnamic acid, Sinapinic acid
• Empirical Formula (Hill Notation): C₁₁H₁₂O₅
• CAS Number: 530-59-6
• Molecular Weight: 224.21
• Beilstein: 2699118
• EC Number: 208-487-3
• MDL number: MFCD00004401
• PubChem Substance ID: 329769377
• NACRES: NA.21

Properties

• grade: matrix substance for MALDI-MS
• Quality Level: 100
• Assay: ≥99.0% (T)
• form: powder
• analyte chemical class(es): dendrimers, fullerenes, peptides, proteins
• technique(s): MALDI-MS: suitable
• color: slightly yellow
• mp: ~202 °C
• solubility: dioxane: 1 g/10 mL at Hot, clear, faintly yellow to dark yellow-orange; dioxane: 1 g/10 mL at Hot, clear, orange to very deep orange
• cation traces: Ba: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤20 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• suitability: in accordance for UV test
• SMILES string: COc1cc(\C=C\C(O)=O)cc(OC)c1O
• InChI: 1S/C11H12O5/c1-15-8-5-7(3-4-10(12)13)6-9(16-2)11(8)14/h3-6,14H,1-2H3,(H,12,13)/b4-3+
• InChI key: PCMORTLOPMLEFB-ONEGZZNKSA-N

Description

General description

Sinapic acid is a type of phenolic acid. Removal of amino group from phenylalanine, catalysing with enzyme phenylalanine ammonia-lyase forms cinnamic acid. The precursor of hydroxycinnamates is produced after hydroxylation of benzene ring. One of the precursors produced is sinapic acid.

Application

Sinapic acid was suitable as phenolic standard for HPLC analysis in determination of Sinapic acid derivatives in Canola extracts. 10 g/L of sinapinic acid with solvent was suitable as matrix for ultraviolet laser desorption mass spectrometric determination of proteins. It was also suitable to use as matrix for MALDI-TOFMS and MALDI-ion mobility-TOFMS to determine phospholipids in tissue.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves