All Photos(3)



Span® 80

greener alternative

viscosity 1000-2000 mPa.s (20 °C)

Span 80, Sorbitan monooleate
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:



Quality Level

mol wt

428.60 g/mol

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

refractive index

n20/D 1.48 (lit.)


1000-2000 mPa.s(20 °C)

HLB value



0.99 g/mL at 20 °C
0.986 g/mL at 25 °C (lit.)

greener alternative category


SMILES string




InChI key


Looking for similar products? Visit Product Comparison Guide

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is biodegradable surfactant, thus aligns with "Use of Renewable Feedstocks" and "Design for Degradation" principles of Green Chemistry, and belongs to "12 principles aligned" category of our greener alternatives.
Span® 80 is a sorbitan ester series of surfactant. It is produced by esterification of one or more sorbitan hydroxyl group with fatty acid. It is hydrophobic in nature. This non-ionic surfactant can be used to form oil-in-water emulsions and in combination with low HLB surfactants can form water-in-oil emulsions. EPA approved oil spill dispersant.


Span® 80 was suitable as surfactant in the preparation of Poly(divinylbenzene) emulsion-derived (PolyHIPE) solid foam. It may be suitable as emulsifier used to extract 24 samples of emulsion explosives with hexane which were analysed using GC-MS.

Legal Information

Span is a registered trademark of Croda International PLC

Storage Class Code

12 - Non Combustible Liquids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Fei-Fei Tian et al.
Journal of chromatography. A, 1218(22), 3521-3528 (2011-04-19)
A novel approach for identification and determination of emulsion explosives with Span-80 (sorbitol mono-oleate) as the emulsifier and their postblast residues by gas chromatography-mass spectrometry (GC-MS) has been developed. 24 kinds of emulsion explosives collected have been processed by transesterification
Morphology and surface area of emulsion-derived (PolyHIPE) solid foams prepared with oil-phase soluble porogenic solvents: Span 80 as surfactant.
Barbetta, Andrea, and Neil R. Cameron
Macromolecules, 37, 3188-3201 (2004)
Michael E. Aulton, Kevin M.G. Taylor
Aulton's Pharmaceutics: The Design and Manufacture of Medicines, 445-445 (2013)
Geneviève LeBel et al.
Applied and environmental microbiology, 80(17), 5484-5492 (2014-06-29)
Streptococcus suis serotype 2 is known to cause severe infections (meningitis, endocarditis, and septicemia) in pigs and is considered an emerging zoonotic agent. Antibiotics have long been used in the swine industry for disease treatment/prevention and growth promoters. This pattern
Daan Vorselen et al.
Nature communications, 11(1), 20-20 (2020-01-09)
Force exertion is an integral part of cellular behavior. Traction force microscopy (TFM) has been instrumental for studying such forces, providing spatial force measurements at subcellular resolution. However, the applications of classical TFM are restricted by the typical planar geometry.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service