PHR1086

Acetanilide melting point standard

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Acetanilide, N-Phenylacetamide
• Linear Formula: CH₃CONHC₆H₅
• CAS Number: 103-84-4
• Molecular Weight: 135.16
• Beilstein: 606468
• EC Number: 203-150-7
• MDL number: MFCD00008674
• eCl@ss: 39031308
• PubChem Substance ID: 329823108
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to USP 1004001
• vapor density: 4.65 (vs air)
• vapor pressure: 1 mmHg ( 114 °C)
• CofA: current certificate can be downloaded
• autoignition temp.: 1004 °F
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• bp: 304 °C (lit.)
• mp: ~Approximately 115 °C; 113-115 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC(=O)Nc1ccccc1
• InChI: 1S/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)
• InChI key: FZERHIULMFGESH-UHFFFAOYSA-N

Description

General description

Acetanilide belongs to a class of compounds which are the active components of drugs exhibiting analgesic and antipyretic properties.[1][2]

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Acetanilide has been used as a calibration standard for the development of a test for the evaluation of acetanilide by thermal analyses methods.[3][1]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7127 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): 321.8 °F - closed cup
• Flash Point(C): 161 °C - closed cup