Merck
All Photos(1)

04276

Sigma-Aldrich

Sodium phosphate dibasic

puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E 339, anhydrous, 98-100.5% (calc. to the dried substance)

Synonym(s):
Sodium hydrogenphosphate, Disodium phosphate, Disodium hydrogen phosphate, sec-Sodium phosphate
Linear Formula:
Na2HPO4
CAS Number:
Molecular Weight:
141.96
EC Number:
MDL number:
eCl@ss:
38070211
PubChem Substance ID:
NACRES:
NA.25

Agency

meets analytical specifications of BP
meets analytical specifications of Ph. Eur.
meets analytical specifications of USP

grade

puriss.

assay

98-100.5% (calc. to the dried substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, USP, FCC, E 339

impurities

reducing matter, complies
residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.002% ammonium (NH4)
≤0.2% water-insoluble matter
≤1% NaH2PO4 (calc. to dried subst.)
≤2.0% pyrophosphate (as Na4P2O7)

loss

≤1% loss on drying, 105°C, 4h
≤1% loss on drying, 130 °C

pH

8.4-9.6 (20 °C, 1%)

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

solubility

H2O: soluble 8 parts
H2O: very soluble (Hot)
alcohol: insoluble

anion traces

chloride (Cl-): ≤50 mg/kg
fluoride (F-): ≤10 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤10 mg/kg
Fe: ≤20 mg/kg
Hg: ≤1 mg/kg
Pb: ≤4 mg/kg
Zn: ≤10 mg/kg

suitability

complies for appearance of solution

SMILES string

[Na+].[Na+].[H]OP([O-])([O-])=O

InChI

1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2

InChI key

BNIILDVGGAEEIG-UHFFFAOYSA-L

Looking for similar products? Visit Product Comparison Guide

Application

Sodium phosphate dibasic has been used for preparing phosphate buffer which in turn is utilized in X-gal staining.

Biochem/physiol Actions

Sodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More documents

Quotes and Ordering

Noriko Tsuchiya et al.
Toxicologic pathology, 32(4), 408-412 (2004-06-19)
To elucidate the nephrotoxicity of phosphate, dibasic sodium phosphate solution was given to Sprague-Dawley rats by daily bolus intravenous administration at concentrations of 0, 1, 25, 250, or 360 mM (0, 1, 28, 284, or 408 mg/kg Na2HPO4) for 14
B Duvillié et al.
Endocrinology, 143(4), 1530-1537 (2002-03-19)
The targeted disruption of the two nonallelic insulin genes in mouse was reported previously to result in intrauterine growth retardation, severe diabetes immediately after suckling, and death within 48 h of birth. We have further used these animals to investigate
Noriko Tsuchiya et al.
Toxicologic pathology, 37(3), 270-279 (2009-02-27)
Sprague-Dawley rats received once daily tail-vein injections of 360 mM dibasic sodium phosphate solution at 8 mL/kg for fourteen or twenty-eight days. Clinical examination revealed persistent proteinuria from three days after the first dosing and thereafter severe proteinuria from eight
Samuel Adler et al.
Gastrointestinal endoscopy, 76(6), 1170-1174 (2012-10-03)
Colon capsule endoscopy (CCE) is a noninvasive technique for the detection of colorectal lesions. However, for CCE to be offered as an out-of-clinic procedure, the system needs to automatically alert the patient when to ingest the laxative (booster). We tested
Megan A Rees et al.
Journal of proteome research, 14(1), 120-132 (2014-10-21)
Interactions between a host and a bacterial pathogen are mediated by cross-talk between molecules present on, or secreted by, pathogens and host binding-molecules. Identifying proteins involved at this interface would provide substantial insights into this interaction. Although numerous studies have

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service