237213

Sodium nitrite

ACS reagent, ≥97.0%

• Linear Formula: NaNO₂
• CAS Number: 7632-00-0
• Molecular Weight: 69.00
• EC Number: 231-555-9
• MDL number: MFCD00011118
• PubChem Substance ID: 329752451
• NACRES: NA.21

Properties

• grade: ACS reagent
• Quality Level: 200
• Assay: ≥97.0%
• form: powder or crystals
• autoignition temp.: 914 °F
• impurities: ≤0.01% insolubles
• mp: 271 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.01%
• cation traces: Ca: ≤0.01%; Fe: ≤0.001%; K: ≤0.005%; heavy metals (as Pb): ≤0.001%
• SMILES string: [Na+].[O-]N=O
• InChI: 1S/HNO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1
• InChI key: LPXPTNMVRIOKMN-UHFFFAOYSA-M

Description

General description

Sodium nitrite (NaNO₂) is an inorganic compound that is commonly used as a reagent and catalyst in synthetic organic chemistry.

Application

Co-catalyst for catalytic oxidation of alcohols under aerobic, solvent-free conditions.

Solvent free aerobic oxidation of alcohols with 1-methyl-2-azaadamantane N-oxyl as a recyclable catalyst through phase separation

Sodium nitrite can be used as a reagent in:      

• The Sandmeyer reaction for converting amines into diazo derivatives, and nitration reaction.      
• The oxidative C-C bond formation reaction in the presence of oxygen as the terminal oxidant.      
• The oxidative carbonitration of alkenes in the presence of K₂S₂O₈.

It can also be used as a nitrating agent in organic synthesis. For example, NaNO₂ is used in direct C-H nitration, ipso-nitration, and nitration via transition metal-catalyzed cross-coupling reaction.

Safety Information

• Pictograms: GHS03,GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H272 - H301 - H319 - H400
• Precautionary Statements: P210 - P220 - P264 - P273 - P301 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Ox. Sol. 3
• Storage Class Code: 5.1B - Oxidizing hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable