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Ethyl acetate

suitable for HPLC, ≥99.7%

Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

vapor density

3 (20 °C, vs air)

vapor pressure

73 mmHg ( 20 °C)





autoignition temp.

801 °F

expl. lim.

2.2-11.5 %, 38 °F


GC/MS: suitable
HPLC: suitable


≤0.0005% non-volatile matter
≤0.005% free acid (as CH3COOH)
≤0.03% water (Karl Fischer)

refractive index

n20/D 1.3720 (lit.)


76.5-77.5 °C (lit.)


−84 °C (lit.)


0.902 g/mL at 25 °C (lit.)

UV absorption

λ: 255 nm Amax: ≤0.70
λ: 260 nm Amax: ≤0.30
λ: 270 nm Amax: ≤0.10
λ: 300 nm Amax: ≤0.01
λ: 400 nm Amax: ≤0.01


food and beverages

SMILES string




InChI key


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General description

Ethyl acetate is an effective alternate solvent of diethyl ether.


Ethyl acetate has been used as solvent for the isolation of Rose hip (Rosa canina L., Rosaceae) powder, via sonication. It has been used as solvent for the abstraction of volatile thiols from wine for their quantitative estimation by gas chromatography/mass spectrometry (GC-MS).


1, 6×1, 2, 4×2, 4×2.5, 4, 4×4 L in glass bottle
1 pkg in Pure-Pac™ 2
200 L in Pure-Pac™ 1
18 L in Pure-Pac™ 1
100 mL in glass bottle
20, 50 L in Pure-Pac™ 2

Other Notes

Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.
Important notice
  • The article number 34858-4X2.5L will be discontinued. Please order the single bottle 34858-2.5L which is physically identical with the same exact specifications.
  • The article number 34858-6X1L will be discontinued. Please order the single bottle 34858-1L which is physically identical with the same exact specifications.

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Legal Information

Pure-Pac is a registered trademark of Sigma-Aldrich Co. LLC


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Signal Word


Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids



Flash Point(F)

24.8 °F

Flash Point(C)

-4 °C

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Maria Nikolantonaki et al.
Analytica chimica acta, 660(1-2), 102-109 (2010-01-28)
As volatile thiols are nucleophiles, they are capable of additional reactions with electrophiles. In enology, this concerns reactions between volatile or non-volatile thiols and oxidized phenolic compounds. Initial studies concerning the reactivity of volatile thiols with polyphenols showed that (+)-catechin
Lasse Saaby et al.
Phytotherapy research : PTR, 25(2), 195-201 (2010-07-16)
A previously published systematic review and a metaanalysis have concluded that the consumption of standardized rose hip powder (Rosa canina L.) can reduce pain in osteoarthritis patients. Synovial inflammation has been suggested to play an important role in the pathogenesis
Jessica Le Ven et al.
Journal of mass spectrometry : JMS, 47(11), 1500-1509 (2012-11-14)
Annonaceous acetogenins (AAGs) are a homogenous class of polyketides proposed as environmental neurotoxins. Previous dereplication studies of AAGs were limited by the use of low-resolution mass spectrometers. Only poor information in terms of structures was provided due to the limited
Tsukasa Horiyama et al.
PloS one, 9(9), e108642-e108642 (2014-09-27)
Escherichia coli produces the iron-chelating compound enterobactin to enable growth under iron-limiting conditions. After biosynthesis, enterobactin is released from the cell. However, the enterobactin export system is not fully understood. Previous studies have suggested that the outer membrane channel TolC
Flavio G Rocha et al.
Biomaterials, 29(19), 2884-2890 (2008-04-09)
Our group has previously created a functional neointestine that is capable of restoring absorptive function. However, the endogenous level of vascular endothelial growth factor (VEGF) is markedly reduced in the construct compared to native bowel. Therefore, we wanted to locally


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